Tumor angiogenesis is closely associated with clinical staging and has been proposed to correlate with clinical response in terms of subsequent metastases following primary resection. Netrin-4 (NT-4) regulates angiogenic responses. Therefore, we sought to examine the effects of NT-4 on the primary tumor growth of colon cancer cells, liver and lung...

BACKGROUND AND STUDY AIMS We present a case of invasive micropapillary carcinoma (IMPC) of the colon treated by endoscopic resection following magnifying endoscopy. A 47-year-old woman visited our hospital for follow-up of a positive fecal occult blood test. Colonoscopy revealed a semi-pedunculated reddish polyp, the surface of which showed gentle irregularity, and mild tension in the sigmoid c...

Endoscopic submucosal dissection (ESD) was first implemented in early gastric cancer allowing for en-bloc resection of the lesions. With the experience came the expertise to introduce ESD for early colon cancer (ECC). ESD demonstrates several advantages in comparison with the endoscopic mucosa resection. It allows accurate histological assessment of the depth of invasion, minimizes the risk of ...

We report a case of early gastric cancer and early colon cancer detected by positron emission tomography (PET) cancer screening. A 64-year-old male patient with an unremarkable past history except for hypertension and cerebrovascular disease underwent 18F-FDG PET for cancer screening. Images revealed increased uptake in the gastric antrum and sigmoid colon. Both areas appeared suspicious for ne...

BACKGROUND There were only few case reports in which CTC was performed in patients with colostomy. CASE PRESENTATION A 68-year-old man was admitted with right abdominal pain and bloody stool that had been present for 2 weeks prior to admission. His medical history included abdominoperineal rectal resection with permanent sigmoid stoma (Miles operation). Colonoscopy showed a sub-occlusive tumo...

Lipomas are the most frequent benign tumours of the digestive tract and 50% are localized in the colon. Most are found in the submucosa and may vary in their incidence, localization, symptoms and pathogenesis. We present the case of a 49-year-old female with intermittent intestinal subocclusion, abdominal distention and intussusception. Colonoscopy disclosed a submucous tumour in the descending...

BACKGROUND Hirschsprung's disease is a congenital disorder which is rare in adulthood. In typical cases the aganglionosis involves mainly the rectum or rectosigmoid colon and the lesion starts from the anal valve. Zonal segmental aganglionosis is a very rare type even in children. PATIENT A 54 year old women with zonal segmental aganglionosis had an aganglionic segment 18 cm in length located...

Abstract Objectives Colon cancer patients were analyzed to compare the effects of surgical trauma on immune function by detecting activation degree cell inflammatory cytokines levels after different procedures. Methods In total, 107 with colon divided into open surgery group and laparoscopic group. Serum tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), toll-like receptor 4 (TLR4), cluster...

AbstractBackground The aim of the study was to analyze clinical characteristics and outcomes patients with de novo secondary adenocarcinoma arising in operatively transposed colon not exposed fecal stream. Methods Two investigators collected reviewed papers from June 1938 2019, reporting colon, contact Results Overall, we identified 98 a colonic autograft, po...

PURPOSE The aim of this study was to assess the feasibility and safety of laparoscopic resection following the insertion of self-expanding metallic stents (SEMS) for the treatment of obstructing left-sided colon cancer. METHODS Between October 2006 and December 2012, laparoscopic resection following SEMS insertion was performed in 54 patients with obstructing left-sided colon cancer. RESULT...