Verbal memory (VM) represents one of the most affected cognitive domains in schizophrenia. Multiple studies have shown that schizophrenia is associated with cortical abnormalities, but it remains unclear whether these are related to VM impairments. Considering the vast literature demonstrating the role of the frontal cortex, the parahippocampal cortex, and the hippocampus in VM, we examined the...

Three persons with severe physical and cognitive impairments, residents of a facility for persons with mental retardation, learned to use switch-controlled assistive devices. Previous case reports have described the technology and techniques used to enable these women to explore their surroundings. Material was collected, organized, and analyzed in three sections: clients, powered devices, and ...

Several researchers argue that age related cognitive impairments have detrimental affect on use of web services by older adults. However little and systematic applied research has been conducted on how age related cognitive impairments might affect the usage of web services by older adults. Undoubtedly, understanding the relationship between the cognitive changes that accompany aging and their ...

INTRODUCTION we have tested the hypothesis that the co-occurrence of common impairments (motor and cognitive impairments, vision and hearing loss, depressive symptoms) of later life have exacerbating effects on disability [activities and instrumental activities of daily living, social and role function, (in)activity]. METHOD data were drawn from a community-based sample of 624 people aged 57 ...

This paper discusses impairments of high-level, complex language production in Parkinson's disease (PD), defined as sentence and discourse production, and situates these impairments within the framework of current psycholinguistic theories of language production. The paper comprises three major sections, an overview of the effects of PD on the brain and cognition, a review of the literature on ...

One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...

Introduction: Previous studies demonstrated that forced and voluntary exercise had ameliorative effects on behavioral tasks followed by Sleep Deprivation (SD) in intact female rats. The main goal of this research was evaluating the impact of voluntary exercise on cognitive functions while SD and ovariectomization is induced in female wistar rats. Methods: The rats were anesthesized combining d...

P atients, their families, and physicians are increasingly concerned with cognitive, functional, and psychological outcomes of chronic and acute medical conditions. This has lead to increased emphasis on patient-reported outcomes (PROs), such as quality of life (QoL), depression, anxiety and functional and cognitive status, in observational studies. In addition, the consolidated standards of re...

White matter lesions are often seen in children with spastic cerebral palsy (CP). Evidence points to specific impairment of attentional, visuospatial, and executive functions; although both attention and executive functions are relatively unexplored in spastic CP. The few recent studies on language functions in mild or moderate CP point to well-functioning language. The presence of specific cog...

AIM In contrast with findings in amyotrophic lateral sclerosis (ALS), cognitive impairments have as yet not been shown in the lower motor neuron variant of motor neuron disease, progressive spinal muscular atrophy (PMA). The objective of this study was to investigate cognitive function in PMA and to compare the cognitive profile with that of ALS. In addition, visuospatial functions were assesse...