Compared to other primates, humans live a long time and have large brains. Recent theories of the evolution of human life history stages (grandmother hypothesis, intergenerational transfer of information) lend credence to the notion that selection for increased life span and menopause has occurred in hominid evolution, despite the reduction in the force of natural selection operating on older, ...

Cognitive disorders can be associated with brain trauma, neurodegenerative disease or as a part of physiological aging. Aging in humans is generally associated with deterioration of cognitive performance and, in particular, learning and memory. Different therapeutic approaches are available to treat cognitive impairment during physiological aging and neurodegenerative or psychiatric disorders. ...

Studies have identified generalized slowing in information processing speed as the primary cognitive deficit in multiple sclerosis (MS). Similar changes are also commonly observed in healthy cognitive aging. The present study is the first to examine the combined impact of aging and disease on the course of cognitive slowing. MS patients (N = 245) and healthy controls (N = 188) were assessed usi...

Type 1 diabetes is associated with cognitive changes in children and adults, but the extent to which cognition declines with increasing age, and increasing duration of diabetes, remains poorly understood. This cross-sectional study assessed neuropsychological performance on 200 diabetic and 175 nondiabetic adults, 18-64 years of age, stratified into five age bands. Similar age-related cognitive...

Recent evidence suggests a positive impact of bilingualism on cognition, including later onset of dementia. However, monolinguals and bilinguals might have different baseline cognitive ability. We present the first study examining the effect of bilingualism on later-life cognition controlling for childhood intelligence. We studied 853 participants, first tested in 1947 (age = 11 years), and ret...

Timothy Salthouse's main goal in this book is to try to identify some of the major phenomena in the field of cognitive aging, and discuss issues relevant to the investigation and interpretation of them. He does not attempt to provide a comprehensive survey of the research literature on aging and cognition because many excellent reviews are available in edited handbooks. His principal aim is rat...

With ever-increasing elder population, the high incidence of age-related diseases such as neurodegenerative disorders has turned out to be a huge public concern. Especially the elders and their families dreadfully suffer from the learning, behavioral and cognitive impairments. The lack of effective therapies for such a horrible symptom makes a great demanding for biological mechanism study for ...

Timothy Salthouse's main goal in this book is to try to identify some of the major phenomena in the field of cognitive aging, and discuss issues relevant to the investigation and interpretation of them. He does not attempt to provide a comprehensive survey of the research literature on aging and cognition because many excellent reviews are available in edited handbooks. His principal aim is rat...

Increasing the lifespan of a population is often a marker of a country's success. With the percentage of the population over 65 yr of age expanding, managing the health and independence of this population is an ongoing concern. Advancing age is associated with a decrease in cognitive function that ultimately affects quality of life. Understanding potential adverse effects of aging on brain bloo...

Timothy Salthouse's main goal in this book is to try to identify some of the major phenomena in the field of cognitive aging, and discuss issues relevant to the investigation and interpretation of them. He does not attempt to provide a comprehensive survey of the research literature on aging and cognition because many excellent reviews are available in edited handbooks. His principal aim is rat...