BACKGROUND Coffee has been reported to lower levels of estrogen and insulin, two hormones implicated in endometrial carcinogenesis, but prospective data on the relation between coffee consumption and risk of endometrial cancer are limited. METHODS We prospectively assessed coffee consumption in relation to endometrial cancer risk in the Nurses' Health Study (NHS) with 67,470 female participan...

In this work, we evaluated the occurrence of furan in brews obtained from regular, decaffeinated, and instant coffee and commercial packed capsules. For this purpose, a previously developed automated headspace solid-phase microextraction method coupled to gas chromatography-mass spectrometry (HS-SPME-GC-MS) was used. Initially, the influence of HS-SPME conditions on furan formation was evaluate...

BACKGROUND Cigarettes and coffee are widely used psychoactive substances among alcoholics. Due to the devastating public health impact of alcohol use disorders, it is important to determine if using cigarettes or coffee may influence alcoholism. Previous studies indicate that cigarette smoking is associated with progression of alcohol dependence, but the effects of coffee drinking have yet to b...

Epidemiological studies indicate a J-shaped relationship linking coffee consumption and cardiovascular risk, suggesting that moderate coffee consumption can be beneficial. Platelet aggregation is of critical importance in thrombotic events, and platelets play a major role in the aetiology of several CVD. The aim of this study was to evaluate the effect of coffee drinking on platelet aggregation...

BACKGROUND Coffee consumption has been associated with a lower risk of type 2 diabetes in prospective cohort studies, but the underlying mechanisms remain unclear. The aim of this study was to evaluate the effects of regular and decaffeinated coffee on biological risk factors for type 2 diabetes. METHODS Randomized parallel-arm intervention conducted in 45 healthy overweight volunteers who we...

The R-Coffee web server produces highly accurate multiple alignments of noncoding RNA (ncRNA) sequences, taking into account predicted secondary structures. R-Coffee uses a novel algorithm recently incorporated in the T-Coffee package. R-Coffee works along the same lines as T-Coffee: it uses pairwise or multiple sequence alignment (MSA) methods to compute a primary library of input alignments. ...

The impact and cost of synthetic fertilizers as well as their associated risks on the environmental safety was becoming unaffordable. To alleviate these problems, integrating this synthetic fertilizers with easily available and an environment friendly compound like bio-char is of very high significance towards meeting our goal of increasing agricultural production and ensuring food security. Th...

Introduction: Persistent postinfectious cough (PPC) is a cough that persists longer than 3 weeks or perhaps for many months after a common cold or an upper respiratory tract infection (URTI). PPC has poor response to routine treatment modalities, so it can be a vexing problem for the patient and the physician alike. Our hypothesis was that honey and/or coffee have some beneficial effects in th...

(continued on page 38) Coffee drinking is almost universal. Caffeine, a major component of coffee and to some extent tea, is known to have a transient stimulatory effect. While unpleasant side effects such as nervousness, palpitations, sleeplessness, and cardiac arrhythmias are better known, coffee is also gaining a reputation as a functional food. In particular coffee consumption is noted to r...

Coffee (Coffea arabica L.) is the most extensively consumed beverage in the world. It is grown throughout many regions of the world, including Central Africa, Asia, and Central and South America. Brazil, Vietnam, and Colombia produce about 45% of the world’s coffee. Colombia grows coffee on 2.3 million acres and supplies 10% of the world’s coffee demand. Colombian coffee is also recognized as h...