1792. Higher Adherence to an Inpatient Treatment Guideline for Communityacquired Pneumonia is Associated with Reduced Mortality in Botswana Michelle Haas, MD; Raina Phillips, MD; Harvey Friedman, MD; Bakgaki Ratshaa,; Ari Ho-Foster, MSc; Medicine/Infectious Diseases, Denver Health Medical Center, Denver, CO; Medicine/Infectious Diseases, University of Colorado-Denver Health Sciences Center, Den...

results of all participants, 104 patients (52%) were diagnosed with cmv infection. there was no significant difference between the two groups, with and without cmv infection, in terms of patient’s characteristics. the cmv infection, in patients receiving a transplanted organ from deceased donor, was significantly more prevalent than in those receiving kidney transplant from living donor (63% vs...

influenza Suchitra Rao, MB, BS; Michelle Torok, PhD; Joshua Williams, MD; Maureen Cunningham, MD; Mary Glode, MD, FIDSA; Karen Wilson, MD, MPH; Pediatrics (Infectious Diseases), University of Colorado School of Medicine, Aurora, CO; University of Colorado School of Medicine, Aurora, CO; Children’s Outcomes Research Program/Colorado Health Outcomes Program, Aurora, CO; Pediatrics, University of ...

209. Results of an Antimicrobial Stewardship Intervention Involving Surgical Subspecialty Patients Kati Shihadeh, PharmD; Michelle Haas, MD; Philip Mehler, MD; Marcia Eustaquio, MD; Timothy Jenkins, MD; University of Colorado Skagg’s School of Pharmacy and Pharmaceutical Sciences, Aurora, CO; Acute Care Pharmacy, Denver Health Medical Center, Denver, CO; Medicine/Infectious Diseases, Denver Hea...

BACKGROUND Cytomegalovirus reactivation occurs within 6 months in 60-70% of cytomegalovirus-seropositive patients after allogeneic haemopoietic stem-cell transplantation (HSCT), mainly due to immunosuppression associated with the procedure. Pre-emptive antiviral therapy reduces incidence of cytomegalovirus disease but can be toxic. To reduce the potential for disease and subsequent need for suc...

A high particle to infectivity ratio is a feature common to many RNA viruses, with ~90-99% of particles unable to initiate a productive infection under low multiplicity conditions. A recent publication by Brooke et al. revealed that, for influenza A virus (IAV), a proportion of these seemingly non-infectious particles are in fact semi-infectious. Semi-infectious (SI) particles deliver an incomp...

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveo...