PURPOSE This study was designed to improve the in vivo pharmacokinetics of long-circulating vincristine sulfate (VS)-loaded liposomes; three different long-circulating materials, chitosan, poly(ethylene glycol)-1,2-distearoyl sn-glycero-3-phosphatidylethanolamine (PEG-DSPE), and poly(ethylene glycol)-poly-lactide-co-glycolide (PEG-PLGA), were evaluated at the same coating molar ratio with the c...

In this investigation, we have analyzed the structural, electrical, and optical behaviors of pure composite thin films which are obtained from 2D monolayer molybdenum disulfide (MoS 2 ) flakes, conjugated oligomer (CO) 1,4-Bis(9-ethyl-3-carbazo-vinylene)-9,9-dihexyl-fluorene (BECV-DHF), by combining CO (BECV-DHF) with MoS in forms CO/MoS composites. All samples coated on SiO /Si substrates usin...

Nanostructured carbon materials, including carbon nanotubes, membranes, and particles, are an important nanomaterial for many applications in nanoelectronics, sorption and separation, sensors, catalysis, and energy conversion and storage (e.g., double layer capacitors, and hydrogen storage). Varied methods have been developed to synthesize nanostructured carbon materials, such as DC arc-dischar...

Pd+Zr and Pd+Hf co-doped aluminide coatings were deposited on the Mar-M247 nickel superalloy by palladium electroplating followed zirconizing-aluminizing or hafnizing-aluminizing processes. Both consisted of two zones, outer interdiffusion one build ?-(Ni,Pd)Al phase. Hafnium zirconium formed inclusions that precipitated at border zones close to surface (only in Zr+Pd modified coating). Oxidati...

Fibrotic myocardial remodeling is typically accompanied by the appearance of myofibroblasts (MFBs). In vitro, MFBs were shown to slow conduction and precipitate ectopic activity following gap junctional coupling to cardiomyocytes (CMCs). To gain further mechanistic insights into this arrhythmogenic MFB-CMC crosstalk, we performed numerical simulations in cell-based high-resolution two-dimension...

We have studied the formation and the stability of ionomer complexes from grafted copolymers (GICs) in solution and the influence of GIC coatings on the adsorption of the proteins β-lactoglobulin (β-lac), bovine serum albumin (BSA), and lysozyme (Lsz) on silica and polysulfone. The GICs consist of the grafted copolymer PAA(28)-co-PAPEO(22) {poly(acrylic acid)-co-poly[acrylate methoxy poly(ethyl...

We have updated our previous randomised controlled trial comparing release of chromium (Cr) and cobalt (Co) ions and included levels of titanium (Ti) ions. We have compared the findings from 28 mm metal-on-metal total hip replacement, performed using titanium CLS/Spotorno femoral components and titanium AlloFit acetabular components with Metasul bearings, with Durom hip resurfacing using a Meta...

Electrolytic Hard Chrome (EHC) coatings are widely employed to improve the surface performance of engineering components. The superior wear and corrosion resistance, combined with the processing advantage of being able to coat surfaces with complex geometries, makes EHC a preferred choice for coating critical components like aircraft landing gear, hydraulic actuator cylinders, etc. There are, h...

introduction: raisin is a principal traditional export product of iran and has a special position in the foreign trade of the country.during storage, the product turns sticky and hard due to exudates syrup and moisture loss. to solve this problem, the application of edible coating would be an appropriatesolution. edible coating may enhance the boundary layer resistance resulting to the enhanced...