OBJECTIVES Bacterial resistance to antibiotics, driven by antibiotic consumption, imposes a major threat to the effective treatment of bacterial infections. In addition to reducing the amount of antibiotics prescribed, avoiding broad-spectrum antibiotics could extend the lifetime of the current arsenal of antibiotic substances. Therefore, we documented prescriber and patient characteristics ass...

We compared the susceptibility results for 200 clinical anaerobes with nine antibiotics obtained by using a new ATB ANA (bioMérieux) device against those obtained by the National Committee for Clinical Laboratory Standards (NCCLS) standard agar dilution method. For better evaluation of the device, we added some resistant Bacteroides fragilis group strains from our own collection: 3, 6, and 12 s...

Enteroaggregative Escherichia coli (EAEC) is an important agent of diarrhoeal diseases worldwide. The role of EAEC virulence factors in the clinical outcome of infection is not completely defined. This case-control study investigated the prevalence of EAEC, its virulence genes and the antimicrobial resistance profile of adult patients with and without diarrhoea attending three different hospita...

Recent genome-wide association studies identified certain human leukocyote antigen (HLA) alleles as the major risk factors of drug-induced liver injuries (DILI). While these alleles often cause large relative risk, their predictive values are quite low due to low prevalence of idiosyncratic DILI. Finding additional risk factors is important for precision medicine. However, optimal design of fur...

Crude national ambulatory antibiotic dispensing data (2007-2011) of adult patients (aged between 20 and below 65 years) with CAP were obtained and expressed as DDD per 1000 inhabitants and per day (DID). European quality indicators of antibiotic prescribing were calculated and adherence rate to the national CAP guideline was assessed. Antibiotic use for CAP in adults ranged between 0.27 and 0.3...

To identify any difference in the timing of PsA acquisition depending on seasons pre school and older children. pattern symptoms prior to that could be a precursor increasing likelihood being cultured. A retrospective review CF patients (0–18 years) under care RMCH who had first growth or new (being clear for 12 months off treatment) between January 2021 December 2022 was carried out. Growths f...

BackgroundMonitoring the use of antimicrobials in hospitalized patients is critical owing to risk resistance selection. This study aimed describe patterns antimicrobial prescription for most frequent healthcare-associated infections (HAIs) France, relating drugs and microbiological data.MethodsWe used data from 2017 point-prevalence survey HAI a large nationally representative sample inpatients...

Fungi are eukaryotic, heterogeneous, unicellular to filamentous, spore-bearing, and chemoorganotrophic organisms which lack chlorophyll. This present study was carried out isolate identify fungi from petroleum-contaminated soil. Several fungal genera included Rhizopus spp., Mucor Penicillium Rhizoctonia Aspergillus Alternaria Cladosporiumspp. were isolated using potatoes dextrose agar, Czapek-D...

The patient underwent emergency surgical exploration of his perineum, excision of urethra and insertion of a suprapubic catheter by expanding the bladder with the urethral catheter that was placed at admission. The pus-filled collection surrounding the urethra was drained and all necrotic tissue derided. Samples of tissue were sent to the Microbiology Laboratory, isolating Streptococcus miller ...

OBJECTIVES To identify the etiological agent in bacterial conjunctivitis and to determine the antibiogram of bacterial isolates. METHODOLOGY This observational study was conducted at Dr. Essa's Laboratory over a period of 12 months ending in March 2012. Two hundred samples taken from conjunctiva of patients with conjunctivitis were cultured on routine medium and the antibiograms of bacterial ...