Clomiphene Citrate (Clomid, Serophene) was introduced into clinical medicine for the treatment of anovulation in the 1960’s. Its introduction represented a major breakthrough in the medical management for ovulation induction. Prior to Clomiphene, patients with PCOS who were anovulatory had few options besides weight loss and surgical wedge resection of the ovaries. While wedge resection was suc...

ABSTRACTOvulation induction with clomiphene citrate is a hormonal therapy for infertile women impaired ovarian function caused by dysregulation of the hypothalamus and pituitary, affecting egg development ovulation. Several factors, such as obesity, influence success rate treatment citrate. According to Asia-Pacific classification, obesity was classified into two categories, type I (25-29,9 kg/...

Clomiphene Citrate (Clomid, Serophene) was introduced into clinical medicine for the treatment of anovulation in the 1960’s. Its introduction represented a major breakthrough in the medical management for ovulation induction. Prior to Clomiphene, patients with PCOS who were anovulatory had few options besides weight loss and surgical wedge resection of the ovaries. While wedge resection was suc...

Anovulation is a common cause of female subfertility. Treatment of anovulation is aimed at induction of ovulation. In women with clomiphene-citrate resistant WHO group II anovulation, one of the treatment options is ovulation induction with exogenous follicle-stimulating hormone (FSH or follitropin). FSH is derived from urine or is produced as recombinant FSH. Two forms of recombinant FSH are a...

OBJECTIVETo determine the pregnaflcy outcome with letrozole as an ovulation inducing agent in infertile pa tients. METHOD A Randomized clinical trial was conducted on 250infertile patients attending the outpatient department. Letrozole wa s administered as 5 mg tablets from day 3 to 7 of menstruation after a preliminary day 2 LH level and baseline ultrasound. RESULTS Letrozole given alone had a...

BACKGROUND Anti-Müllerian hormone (AMH) has been implicated in the pathogenesis of polycystic ovary syndrome (PCOS). The aim of this study was to measure circulating AMH before laparoscopic ovarian diathermy (LOD) to evaluate its prognostic value for an ovulatory response and to investigate AMH changes after LOD to further explore the effects of LOD. METHODS This prospective study included an...

AIM A few cases of psychosis induced by clomiphene citrate have been described so far. However, data on the prevalence of psychotic symptoms among women treated for infertility are inconclusive. Still a little is known about possible psychiatric complications of medications used in assisted reproduction techniques (ART). We present a case of a patient who developed transient psychotic symptoms ...