نتایج جستجو برای: clinical trial
تعداد نتایج: 1365604 فیلتر نتایج به سال:
In this paper, we investigate a step-stress partially accelerated lifetime test for the four-component hybrid systems with Type-II progressive hybrid censoring scheme while the life time of system component follows exponential failure rate. In many cases, the exact component causing the system failure cannot be identified and the cause of failure is masked. Based on Type-II progressively hybrid...
OBJECTIVE Measures of shoulder function may differ by dominance of affected shoulder, surgical history, gender, or race. We present a technique for determining whether observed differences in function between groups are due to biased test items or real differences in function. STUDY DESIGN AND SETTING Four hundred patients who were receiving rehabilitation for a variety of shoulder impairment...
Properties of Huber's M-estimators based on estimating equations have been studied extensively and are well understood for complete (i.i.d.) data. Although the concepts of M-estimators and in ̄uence curves have been extended for some time by Reid (1981) to incomplete data that are subject to right censoring, results on the general behavior of Mestimators based on incomplete data remain scattered...
A structural multilevel model is presented where some of the variables cannot be observed directly but are measured using tests or questionnaires. Observed dichotomous or ordinal polytomous response data serve to measure the latent variables using an item response theory model. The latent variables can be defined at any level of the multilevel model. A Bayesian procedure Markov chain Monte Carl...
This note discusses and illustrates the use of Weibull probability paper for complete samples and for the special kind of censoring known as type II censoring. In the latter case the observed lifetimes consist of the r lowest values of the sample, the remaining unobserved lifetimes all being higher. Three blanks for 1 Cycle Log, 2 Cycle Log and 3 Cycle Log scales on the measurement abscissa are...
This paper extends previous work on the identification of search models in which observed worker productivity is imperfectly observed. In particular, it establishes that these models remain identified even when employment histories are left-censored (i.e. we do not get to follow workers from their initial job out of unemployment), as well as when workers set different reservation wages from one...
This paper illustrates new hybrid latent variable models that are promising for phenotypical analyses. The hybrid models combine features of dimensional and categorical analyses seen in the conventional techniques of factor analysis and latent class analysis. The paper focuses on the analysis of categorical items, which presents especially challenging analyses with hybrid models and has recentl...
In this paper we consider general Hadamard differentiable functionals φ(ΛR,ΛT ) of the cumulative hazard functions of two samples of randomly right censored data, which can be used for the nonparametric assessment of noninferiority. We prove the consistency of various bootstrap procedures as suggested in Freitag et al. [1] for the practical implementation of tests for this problem.
Currently, the most widely used method in the disease management industry for evaluating program effectiveness is the "total population approach." This model is a pretest-posttest design, with the most basic limitation being that without a control group, there may be sources of bias and/or competing extraneous confounding factors that offer plausible rationale explaining the change from baselin...
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