BACKGROUND Mutations of the MSX1 gene may contribute to non-syndromic forms of cleft lip and/or cleft palate. AIM To search for mutations of MSX1 coding regions, including one highly conserved non-coding region in the single intron, among Chilean patients with cleft lip/palate. PATIENTS AND METHODS We studied 45 patients with cleft lip/palate and their parents. Oral mucosa samples were obta...

Reconstruction of the cleft nasal deformity can often pose a significant challenge to a rhinoplasty surgeon. Principal features of unilateral and bilateral cleft nasal deformities and their changes with growth are discussed. This article reviews current trends in cleft nasal rhinoplasty associated with early and late intervention. Finally, the authors review their own data on the applications o...

INTRODUCTION The anterior mitral leaflet cleft is an unusual congenital lesion most often encountered in association with other congenital heart defects. The isolated anterior leaflet cleft is quite a rare anomaly and is usually cause of mitral valve regurgitation. The importance of the lesion is that it is often correctable. When feasible, cleft suture and, eventually, annuloplasty are prefera...

The aim of this study was to assess the prevalence of caries in children with cleft lip and∕or palate aged 6-36 months of life. This study was conducted at the University of São Paulo School of Dentistry, Brazil. A total of 143 children were selected (73 male, 70 female), all of whom had at least two erupted teeth. The children were distributed as follows: 88 had cleft lip and palate, 35 had cl...

The diversity of secondary deformities following repair of the cleft lip and nose is striking. The deformities reflect the wide variety of surgical techniques used to repair the cleft lip and the cleft lip nose. Secondary deformities of the repaired cleft lip and nose result from several distinct but related components: congenitally abnormal tissues; surgically modified tissues; the innate tend...

background disorders of the palatal uvula is one of the least highlighted areas of medical literature,inspite the fact that uvula is a key organ in functions like speech, deglutition and mastication. the aim of this paper is to present a series of cases of wide range of uvular deformities ranging from bifid uvula to absence of uvula.

Aim : To assess the prevalence of dental caries among cleft lip / cleft palate patients in 35 years of age, at Jain Hospital. Methods: The study sample consisted of 100 children visiting Jain Hospital Bangalore in the age group of 3 to 5 years. Dental caries status was recorded using dmfs index by Grubbel.A.O. Results: Fifty percent of the children had caries and was significantly greater in cl...

The notions of a cleft extension and a cross product with a Hopf algebroid are introduced and studied. In particular it is shown that an extension (with a Hopf algebroid H = (HL,HR)) is cleft if and only if it is HR-Galois and has a normal basis property relative to the base ring L of HL. Cleft extensions are identified as crossed products with invertible cocycles. The relationship between the ...

Submucous cleft palate is a missed or forgotten diagnosis. We reviewed 81 patients with submucous cleft palate seen over a 15 year period; 26 of these patients were interviewed. The patients were divided into three main groups according to the referral pattern. Children under 2.5 years were referred by a paediatrician for feeding problems; children aged 2.5-10 were referred mainly by speech the...

Our purpose was to determine in 20 unilateral cleft lip and alveolus subjects characteristics of the maxillary permanent teeth and maxillary arch development. Clinical and radiographic examinations have been carried out to identify congenitally missing teeth and sagittal skeletal patterns. Study cast assessment was undertaken to evaluate mesiodistal widths of individual teeth, intercanine and i...