نتایج جستجو برای: cladribine

تعداد نتایج: 689  

2010
John R. Corboy

Neurology® Clinical Practice 2010;75(Suppl 1):S22–S27 Care of the patient with multiple sclerosis (MS) is becoming increasingly complex, with new symptomatic therapies (e.g., dalfampridine), enhanced use of disease-modifying therapies that are potentially both more efficacious and more risky (e.g., natalizumab, rituximab) than “standard” immunomodulators, the advent of oral disease-modifying th...

2015
Monica Else Claire E. Dearden Daniel Catovsky

Since 2006 when we last reviewed the literature concerning the use of purine analogues in hairy cell leukaemia (HCL), results from several new and updated series have been published. Here we examine these reports and consider their implications for patient management. The two purine analogues pentostatin and cladribine remain the first-line treatments of choice for all patients with HCL. Althou...

Journal: :Turkish journal of haematology : official journal of Turkish Society of Haematology 2007
Özden Pişkin Mehmet Ali Özcan Güner Hayri Özcan Halil Ateş Fatih Demirkan İnci Alacacıoğlu Bülent Ündar

Fludarabine-containing combinations have additive cell killing against leukemic blasts in vitro. It has also been shown that imatinib mesylate combined with fludarabine or cladribine had an additive effect on CML CFU-GM cells. In this regard, we aimed to investigate the effect of fludarabine-imatinib mesylate combination against CML blastic phase cell lines K562 and Meg-01. XTT test was perform...

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