Sensitivity analysis provides important information on the tolerance to fabrication imperfections for any designed devices. Standard sensitivity analysis relies on the first order partial derivatives of a response function of the device with respect to the design parameters. These derivatives are also useful in the device optimization process when a gradient based optimization method is used. T...

In this work, using the scattering matrix method, we have investigated the transmission coefficients and the thermal conductivity in a double-bend waveguide structure. The transmission coefficients show strong resonances due to the scattering in the midsection of a double-bend structure; the positions and the widths of the resonance peaks are determined by the dimensions of the midsection of th...

A simultaneous embedding with fixed edges (SEFE) of two planar graphs R and B is a pair of plane drawings of R and B that coincide when restricted to the common vertices and edges of R and B. We show that whenever R and B admit a SEFE, they also admit a SEFE in which every edge is a polygonal curve with few bends and every pair of edges has few crossings. Specifically: (1) if R and B are trees ...

A three-dimensional grid-drawing of a graph represents the vertices by distinct points in Z (called grid-points), and represents each edge as a polyline between its endpoints with bends (if any) also at gridpoints, such that distinct edges only intersect at common endpoints, and each edge only intersects a vertex that is an endpoint of that edge. This topic has been previously studied in [1–5]....

UNLABELLED The DNA inter base pair step parameters (Tilt, Roll, Twist, Shift, Slide, Rise) are a standard internal coordinate representation of DNA. In the absence of bend and shear, it is relatively easy to mentally visualize how Twist and Rise generate the familiar double helix. More complex structures do not readily yield to such intuition. For this reason, we developed a plug-in for VMD tha...

The blood-brain barrier (BBB) is formed by brain endothelial cells. Many immortalized brain endothelial cell lines have been established; these have been used as in vitro BBB models. The aim of the present study was to assess the paracellular barrier properties of the immortalized mouse brain endothelial cell lines bEND.3, bEND.5 cells, and mouse brain endothelial cell 4 (MBEC4), and those of t...