To define the range of cardiac involvement in the Churg-Strauss syndrome,M mode, continuous wave Doppler, and cross sectional echocardiograms were recorded in twelve patients with the disorder. The M mode recordings were digitised and the cross sectional images were recorded with standardised gain settings to determine regional myocardial echo amplitude. Left ventricular end diastolic and end s...

Background and Aims: The diagnosis of Churg-Strauss syndrome (CSS), an allergic granulomatosis involving smalland medium-sized vessels, requires the presence of at least four of six criteria including asthma, peripheral eosinophilia, and systemic vasculitis. The gastrointestinal manifestations have never been reviewed. Methods: The 75 articles in the English literature found by electronic searc...

OBJECTIVE Churg-Strauss syndrome (CSS) is a rare form of systemic vasculitis. Previous studies showing cardiac involvement in CSS patients were limited in the number of patients and were often based solely on clinical manifestations. The aim of the present study was to determine in detail the incidence of cardiac involvement in a large population of ambulatory CSS patients. METHODS Thirty-two...

patients are using appropriate pharmacotherapy and are clinically stable, there is understandably a disinclination to titrate therapy downwards, in case one offsets the control of asthma, which has been difficult to attain in the first instance. In conclusion, secondary care physicians need to have a heightened awareness in terms of steppingdown ICS therapy in stable asthmatics. Failing to do s...

A young male with complaints of cough, dyspnea and hemoptysis was admitted. He was using fluticasone propionate and salmeterol for two years for his asthma. Leukotriene receptor antagonist was prescribed two weeks prior to his admission and no reduction of his inhaled steroid therapy was performed. Eosinophil count was detected as 1460/mm³ (15%) and immunoglobulin E level was 547 IU/mL. Thorax ...

We describe the case of a 54-year-old woman with a clinical diagnosis of Churg-Strauss syndrome (CSS). The patient had a fever of unknown origin, severe headache, progressing left ophthalmoplegia, and visual acuity disturbance. MR imaging revealed diffuse and thick hypointense lesions on T2-weighted images in the frontal meninges and anterior falx cerebri with diffuse enhancement. Similar lesio...

A case of Churg-Strauss syndrome causing mesenteric intestinal ischaemia and small bowel necrosis is described in a 29-year-old man. Despite conservative management, the patient's condition deteriorated and he underwent five laparotomies. Small and medium-sized arteries within the mesentery and lymph nodes showed necrotizing vasculitis. Currently he is doing well on oral nutrition and medical m...

KEY CLINICAL MESSAGE The etiology of rash in a given patient can be so varied. Good history-taking is very important to prevent unnecessary work-up. In this patient with Churg-Strauss syndrome, the rash was due to "coining," a traditional practice followed in Southeast Asian community and had no relation to her underlying disease.