OBJECTIVES Patients with chronic granulomatous disease and carrier mothers of patients with chronic granulomatous disease are predisposed to developing various forms of lupus. This disorder is a neutrophil defect in intracellular killing. Abnormal apoptosis has been described. We hypothesized that abnormal apoptosis occurring in neutrophils of patients made them more immunogenic. METHODS Huma...

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer death worldwide [1]. HCC is strongly associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection, which are implicated in about 80% of HCCs in certain geographic area [2]. Risk of HCC is increased 5to 15-fold in chronic HBV carriers [1] and 11.5to 17-fold in HCV-infected...

although liability under general tort and contract law principles is not limited to a certain amount, liability arising under a carriage contract is limited by the majority of international transport conventions and national legislatures and, there are certain reasons given to justify the “essential departure from the current rules of civil law” and it is common for the liability of the carrier...

introduction:owing to its favorable radionuclidic characteristics, such as tl/2 = 6.73 day and eβ (max) = 497 kev and ease of its large-scale production using medium flux research reactors, lutetium-177 (177lu) is an attractive radionuclide for various therapeutic applications. no carrier added (nca) 177lu was obtained by thermal neutron bombardment (4×1013n/cm2.s) of 176yb target through 176yb...