Myeloid/lymphoid neoplasm is a rare malignancy with an aggressive course and rapid transformation to acute myeloid leukemia (AML), or less frequently lymphoblastic (ALL). Cases t(8;22)(p11;q11) BCR-FGFR1 fusion gene may be misdiagnosed chronic (CML), due very similar morphologic clinical profile. We report case of 48-year-old woman who complained weakness gastric pain. She had splenomegaly, eos...

This Adverse Outcome Pathway (AOP) describes the linkages between perturbation of normal topoisomerase II enzyme function and infant leukaemia. Infant leukaemia is a rare haematological disease (1 in 106 newborns, accounting for 10% all childhood acute lymphoblastic leukaemias) developmental origin, manifesting soon after birth (< 1 year old). The present AOP how interference stressors with ...