S. S. Dragomir School of Computer Science and Mathematics, Victoria University, P.O. Box 14428, Melbourne, Victoria 8001, Australia Correspondence should be addressed to S. S. Dragomir, [email protected] Received 13 December 2007; Accepted 29 February 2008 Recommended by Yeol Cho A new sharp bound of the Čebyšev functional for the Riemann-Stieltjes integral is obtained. Applications for ...

BACKGROUND AND PURPOSE We have previously reported the development of CB-25 and CB-52, two ligands of CB1 and CB2 cannabinoid receptors. We assessed here their functional activity. EXPERIMENTAL APPROACH The effect of the two compounds on forskolin-induced cAMP formation in intact cells or GTP-gamma-S binding to cell membranes, and their action on nociception in vivo was determined. KEY RESU...

Investigators have reported improved endurance performance and attenuated post-exercise muscle damage with carbohydrate-protein beverages (CHO+P) versus carbohydrate-only beverages (CHO). However, these benefits have been demonstrated only when CHO+P was administered in beverage-form, and exclusively in male subjects. Thus, the purposes of this study were to determine if an oral CHO+P gel impro...

TNFα is one of the initial and important mediators to activate downstream signaling pathways by binding to trimerized TNFα receptors (TNFR), and thus is an ideal drug target for cancer therapy. Taking advantage of intrinsic homotimerization of the globular domain of adiponectin (gAD), we have developed a novel TNFα antagonist, the trimerized fusion protein named sTNFRII-gAD. However, our previo...

Saunders, M.J., N.D. Luden, and J.E. Herrick. Consumption of an oral carbohydrate-protein gel improves cycling endurance and prevents postexercise muscle damage. J. Strength Cond. Res. 21(3):678–684. 2007.—Investigators have reported improved endurance performance and attenuated postexercise muscle damage with carbohydrate-protein beverages (CHO P) versus carbohydrate-only beverages (CHO). Howe...

begin{abstract} in this paper, we introduce an iterative method for amenable semigroup of non expansive mappings and infinite family of non expansive mappings in the frame work of hilbert spaces. we prove the strong convergence of the proposed iterative algorithm to the unique solution of a variational inequality, which is the optimality condition for a minimization problem. the results present...

Despite their practical and commercial relevance, there are few reports on the kinetics of growth and production of Chinese hamster ovary (CHO) cells-the most frequently used host for the industrial production of therapeutic proteins. We characterize the kinetics of cell growth, substrate consumption, and product formation in naive and monoclonal antibody (mAb) producing recombinant CHO cells. ...

Adaptations to long-term morphine treatment resulting in tolerance are protective by counteracting the consequences of sustained opioid receptor activation. Consequently, the manifestation of specific adenylyl cyclase (AC)-related neurochemical sequelae of long-term morphine treatment should depend on the consequences of short-term mu-opioid receptor (MOR) activation. We tested this by comparin...

BACKGROUND AND PURPOSE Abscesses caused by aerobic bacteria (aerobic abscesses) can simulate intracranial glioblastomas multiforme (GBMs) in MR imaging appearance and single voxel (SV) proton MR spectroscopy of the central cavity. The purpose of our study was to determine whether MR spectroscopic imaging (SI) can be used to differentiate aerobic abscesses from GBMs. Our hypothesis was that meta...