BACKGROUND Chlorhexidine is well known for its antiplaque effect. However, the mouthrinse based chlorhexidine antiplaque efficiency may vary according to the formulation of the final product. The aim of the present study was to compare anti-plaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1%...

The aim of this study was to evaluate the cleaning efficacy of 2% chlorhexidine gluconate gel (CHX) compared to 2.5% sodium hypochlorite solution (NaOCl) associated or not with 17% EDTA used as irrigants during the biomechanical preparation. Fifty freshly extracted single-rooted human teeth with complete apex formation were randomly divided into five groups: G1 - sterile saline, G2 - 2.5% NaOCl...

Aim: To analyze and compare the effectiveness of two antibacterial gels in treatment mucositis. Methods: After signing informed consent, accordance with Helsinki Declaration 1975, revised 2000, 21 patients were included study divided by randomization into groups. At baseline, modified bleeding index (mBI) plaque (PI) values measured, an oral hygiene implant disinfection session was carried out....

In a randomized, double-blind trial, gamma radiation-sterilized, chlorhexidine-coated triple-lumen catheters were compared with uncoated control catheters for their ability to prevent catheter infection in 254 intensive care unit patients. The chlorhexidine coating was not efficacious, and a rabbit model demonstrated that reduction of chlorhexidine activity by gamma radiation sterilization was ...

Chlorhexidine gluconate is an effective bactericidal agent and broad-spectrum antimicrobial drug. It has been extensively researched and is the “gold standard” antimicrobial in oral hygiene. Chlorhexidine is useful in many clinical disciplines including periodontics, endodontics, oral surgery and operative dentistry. Introduction Chlorhexidine gluconate (chlorhexidine) is a broad-spectrum antim...

Editor—We read the article on the national audit conducted by the Royal College of Anaesthetists by Cook and colleagues 1 and congratulate the group on an outstanding piece of work which has enlightened the whole anaesthetic community and no doubt will lead to improved patient safety. We note that the NAP3 audit reinforces that sterile technique in regional anaesthesia is an important aspect of...

BACKGROUND Over the last decade, extremely-drug-resistant (XDR) strains of Klebsiella pneumoniae have emerged worldwide, mainly as a result of patient-to-patient spread. The predominant clone, sequence type 258 (ST258), is associated with high morbidity and mortality, and is a worldwide threat to public health. It was hypothesized that reduced susceptibility to chlorhexidine, the most widely us...

To the Editors:Your concerns regarding the recently published study, ‘‘A randomized trial that compared povidone iodine and chlorhexidine as antiseptics for vaginal hysterectomy,’’ are appreciated. First, by way of clarification, the literature search to which you refer did retrieve studies in which vaginal chlorhexidine had been used. In fact, we found 3 studies (including a total of more than...

INTRODUCTION Prosthetic mesh infection constitutes one of the major complications following hernia repair. Antimicrobial, non-antibiotic biomaterials have the potential to reduce bacterial adhesion to the mesh surface and adjacent tissues while avoiding the development of novel antibiotic resistance. This study assesses the efficacy of presoaking reticular polypropylene meshes in chlorhexidine ...

OBJECTIVES The increasing use of chlorhexidine for methicillin-resistant Staphylococcus aureus (MRSA) decolonization raises concerns about reduced susceptibility. We evaluated the carriage of chlorhexidine resistance genes and chlorhexidine susceptibility in MRSA before and after introduction of an institutional MRSA control programme incorporating chlorhexidine-based decolonization in 2004. ...