GC-MS/FID analysis of the essential oils 10 Thymus species, belonging to Sect. Serpyllum, led identification 118 compounds accounting for 97.79–99.69% total oil. moesiacus, T. jankae, vandasii, longicaulis and sibthorpii were characterized by presence linalool (19.37–35.21%) as major or dominant component, but differed significantly in content other prominent components: linalyl acetate, gerani...

Anti-Wolbachia therapy has been identified as a viable treatment for combating filarial diseases. Phenotypic screening revealed series of pyrazolopyrimidine hits with potent anti-Wolbachia activity. This paper focuses on the exploration SAR this chemotype, improvement metabolic stability and solubility profiles using medicinal chemistry approaches. Organic synthesis enabled functionalization co...

Rosmarinus officinalis is a well-studied species; however, R. essential oil (EO) from West highlands of Algeria was not investigated chemically and biologically. In this context, chemical composition EOs obtained leaves stem were determined by GC/MS analysis their antifungal activity against Fusarium oxysporum f. sp. albedinis (Foa) evaluated. The indicated that monoterpenes the dominant class ...