Renal Cell Carcinoma (RCC), cancer of the tubules kidneys, has historically been one most difficult cancers to treat due its ability remain hidden in body for longer than other and tendency resist traditional forms chemotherapy radiation therapy. However, both nontraditional treatments RCC have seen significant biomedical advancements clinical instances use recent years. In this review, we anal...

Chronic myeloid leukemia is a disease marked by expanded clonal hematopoiesis; it is incurable by chemotherapy or radiation but is cured in a majority of patients receiving bone marrow transplantation from nonidentical sibling donors, an outcome generally attributed to a T cell-mediated graft-versus-leukemia effect. In this report, we examine the effect of the P210BCR-ABL fusion protein of the ...

abstract background: chemotherapy- induced nausea and vomiting (cinv) occur frequently causing problems with an unacceptably high incidence that significantly affect patients' daily functioning and health-related quality of life. the present study was aimed to compare acute cinv for granisetron as 5-ht3 receptor antagonist and metoclopramide in the patients receiving chemotherapeutic regimens i...

BACKGROUND The extent of the adjuvant neck dissection after radiotherapy with or without chemotherapy remains undefined. We investigated whether we could limit neck dissection to levels with positive lymph nodes on CT scan before treatment. METHODS Twenty-one patients' initial diagnostic CT scans were reviewed retrospectively and neck levels were scored positive for malignancy if the respecti...

introduction : oral health is an important aspect of public health which affects people’s quality of life. oral health related quality of life is assessed to evaluate the effect of different diseases on individual’s daily life quality. the aim of this study was to examine the oral health related quality of life in patients with head and neck tumors who received radio and chemotherapy. materials...

BACKGROUND AND PURPOSE Proton radiotherapy has been increasingly utilized to treat pediatric brain tumors, however, limited information exists regarding radiation necrosis among these patients. Our aim was to evaluate the incidence, timing, clinical significance, risk factors, and imaging patterns of radiation necrosis in pediatric patients with brain tumors treated with proton radiation therap...

BACKGROUND The optimal time sequences for chemotherapy and radiation therapy after breast surgery for patients with breast cancer remains unknown. Most of published studies were done for early breast cancer patients. However, in Egypt advanced stages were the common presentation. This retrospective analysis aimed to assess the optimum sequence for our population. METHODS 267 eligible patients...

SUMMARY PT promises to reduce side effects in children with brain tumors by sparing normal tissue compared with 3D conformal or intensity-modulated radiation therapy. Information is lacking about the combined effects of PT and chemotherapy in young children. We describe imaging changes in 8 very young children with localized brain tumors who received PT after chemotherapy. Mostly transient sign...

This article will review the pertinent data on the use of chemotherapy for all stages of pancreatic cancer. For patients with metastatic disease, fluorouracil (5-FU) was the standard of care for several decades until a single randomized trial established that gemcitabine (Gemzar) produced a greater clinical benefit response, median survival, and 1-year survival. Among the currently available ch...

BACKGROUND NUT midline carcinoma is a rare and aggressive genetically characterized subtype of squamous cell carcinoma frequently arising from the head and neck. The characteristics and optimal management of head and neck NUT midline carcinoma (HNNMC) are unclear. METHODS A retrospective review of all known cases of HNNMC in the International NUT Midline Carcinoma Registry as of December 31, ...