The chemometrics version of PLS was developed around 25 years ago to cope with and utilize the rapidly increasing volumes of data produced in chemical laboratories. Since then, the first simple two-block PLS has been extended to deal with non-linear relationships, drift in processes (adaptive PLS), dynamics, and with the situation with very many variables (hierarchical models). Starting from a ...

The intensive research in chemometrics is resulting in continuous development of new concepts and optimization methods. The practical chromatographic optimization examples described in this paper highlight the importance of developing efficient and flexible optimization strategies, which are adapted to the (complex) separation problems encountered in the real chromatographic world. The availabi...

Total white blood cells count is an important diagnostic parameter in both human and veterinary medicines. State-of-the-art performed by flow cytometry combined with light scattering or impedance measurements. Spectroscopy point-of-care has the advantages of miniaturization, low sampling, real-time hemogram analysis. While are proportions, while red bilirubin dominate spectral information, comp...

Background Quartz album is one of the mineral drugs commonly used in Chinese medicine. Different geogenesis led to differences its composition and thus affected clinical efficacy. Mineral medicines are mainly composed inorganic elements, including some heavy metals harmful so their quality control crucial safety. Materials Methods In this study, contents 30 elements 13 batches different origins...