1. The physiological actions of HCN and its salts appear to be due (a) to the ease with which HCN molecules penetrate living cells and then ionizing, exert their influence by means of H ions and CN ions; (b) to the weakness of HCN as an acid, which permits at neutrality or at even slight alkalinity the presence of a considerable amount of free HCN molecules in the presence of their salts; (c) t...

efficient cyclization upon irradiation in acetonitrile to produce the spirocyclic enol ethers or esters 56-59. The ease of formation of the salts coupled with the exceptional chemical efficiencies and structural outcomes of these cyclizations indicates that this methodology will have synthetic utility. The results also demonstrate the importance of trialkylsilyl substituents in electrontransfer...

I t is known that a continuous process takes place in bone whereby mature osteones (Haversian systems) are broken down and new osteones are formed. Historadiographic study has shown that the mineral salts content of osteones increases gradually toward a maximum (1, 2, 8). In order to obtain information on the chemical and physical properties of the growing osteone, we have developed a dissectio...

chemical nature, thermodynamic and kinetic properties of metal cations in aqueous solutions are described and discussed in terms of structural factors controlling physical properties of the systems. The structure of hydrated cations, reaction mechanism of water exchange on the cations, hydrolytic phenomena and acidity of the cations are presented. Correlations between coordination states of the...

This combined experimental, theoretical and comparative study details the syntheses and chemical characterisation of two new energetic polynitromethyl tetrazole derivatives, namely, 2-(2-nitro-2-azapropyl)-5-(trinitromethyl)-2 H-tetrazole and its fluorine-containing analogue 2-(2-nitro-2-azapropyl)-5-(fluorodinitromethyl)-2 H-tetrazole. Their crystal structures and energetic behaviour are compa...

In basic Ayurveda texts, Susruta, Caraka and Vagbhata, some quite specific Salts (Lavanam) have been described and their properties and actions are enumerated. By comparing those accounts with the present methods of preparation, conclusions have been made and evidently spurious methods are pointed out. The reported properties of Saindhava, Samudra, Vida, Sauvarcha, Romaka, Audbhida, Gutika, the...

Coordination of copper (I) and (II) salts to melamine (Mel) produces [CuX(Mel)] [X = Cl (5a), Br (5b), I (5c), NO3 (5d)], [CuX2(Mel)2] Æ S [X = Cl, S = H2O (6a); X = Cl, S = 2 MeOH (6b); X = Br, S = 1/2H2O (6c); X = OAc, S = none (6d)], and [Cu(OAc)2(Mel)] (7). The chemical identity of the complexes has been confirmed by elemental analysis, X-ray powder diffraction, thermogravimetry, and infrar...

We wish to thank Mr G. T. Iles of Belle Vue, Manchester, for supplying us with the sample of python fat used in this investigation, and for the information concerning the animal; also Prof. J. W. Cook, F.R.S., for drawing our attention to the work on bile salts; the University of Glasgow for a scholarship held by one of us (R.P.P.) and Imperial Chemical Industries Ltd., for a grant towards the ...

A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies. The analytical data and the chemical properties of the compound sugggested that the endogenous activator of glucuronide formation in rat liver might be uridine diphospha...