OBJECTIVE To investigate whether population based primary prevention (risk factor reduction in apparently healthy people) might be more powerful than current government initiatives favouring risk factor reduction in patients with coronary heart disease (CHD) (secondary prevention). DESIGN, SETTING, AND PARTICIPANTS The IMPACT model was used to synthesise data for England and Wales describing ...

a total of 14 cases of infective endocarditis (ie) in children aged 6 months to 10 years were seen from december 1987 to december 1992 at the pediatric unit of ayatollah taleghani medical center. the majority of patients (12 of 14) were between 5 and 10 years of age. acyanotic congenital heart disease was known to preexist in 78.6% and rheumatic valvular heart disease in 21.4% of cases. organis...

Objective: To determine the dental health of children with Congenital Heart Diseases (CHD) and to evaluate parents’ knowledge importance oral risk Bacterial Endocarditis. Material Methods: This research included 140 divided into study group (80 CHD) control (60 healthy children). The were from different parts Kosova, aged between 3-15. parents asked complete a questionnaire containing demograph...

Background: Reversibility of pulmonary hypertension (PH) is closely related to the treatment options for and prognosis children with congenital heart disease. Objective: We combined patient-specific clinical features including diagnosis, age echocardiographic results, biomarkers vascular dysfunction explore noninvasive methods that can be used accurately evaluate reversibility in disease (PH-CH...

OBJECTIVES Our objective was to prospectively examine the relation between vitamin C intake and risk of coronary heart disease (CHD) in women. BACKGROUND Results from prospective investigations of the relation between vitamin C intake and risk of CHD have been inconsistent. The lack of clear evidence for a protective association despite a plausible mechanism indicates the need to evaluate fur...

BACKGROUND Whether soy food consumption may protect against coronary heart disease (CHD) remains controversial. No previous study has used biomarkers of soy intake in assessing the relationship between soy consumption and CHD. Biomarkers that reflect both intake and metabolism may be more informative than self-reports of dietary intake. METHODS We examined associations of urinary isoflavonoid...

BACKGROUND Exposure to combination antiretroviral therapy (cART) can lead to important metabolic changes and increased risk of coronary heart disease (CHD). Computerized clinical decision support systems have been advocated to improve the management of patients at risk for CHD but it is unclear whether such systems reduce patients' risk for CHD. METHODS We conducted a cluster trial within the...

OBJECTIVES We sought to investigate the pattern of recurrence of congenital heart disease (CHD) where there is one or more affected first-degree relative. BACKGROUND There are little data on patterns of recurrence of different types of CHD. Analysis of a fetal series allows a high ascertainment of affected cases. METHODS We performed an analysis of referrals for detailed fetal echocardiogra...