Adult neurogenesis occurs in neural stem cell (NSC) niches where slow cycling stem cells give rise to faster cycling progenitors. In the adult mouse NSC niche thyroid hormone, T3, and its receptor TRα act as a neurogenic switch promoting progenitor cell cycle completion and neuronal differentiation. Little is known about whether and how T3 controls proliferation of differentially cycling cells ...

Comprehensive, automated software testing requires an oracle to check whether the output produced by a test case matches the expected behavior of the program. But the challenges in creating suitable oracles limit the ability to perform automated testing in some programs, and especially in scientific software. Metamorphic testing is a method for automating the testing process for programs withou...

Metamorphic Testing Techniques to Detect Defects in Applications without Test Oracles Christian Murphy Applications in the fields of scientific computing, simulation, optimization, machine learning, etc. are sometimes said to be “non-testable programs” because there is no reliable test oracle to indicate what the correct output should be for arbitrary input. In some cases, it may be impossible ...

DURING METAMORPHOSIS, THE TRANSITION FROM THE LARVA TO THE ADULT, THE INSECT BRAIN UNDERGOES CONSIDERABLE REMODELING: new neurons are integrated while larval neurons are remodeled or eliminated. One well acknowledged model to study metamorphic brain development is the sphinx moth Manduca sexta. To further understand mechanisms involved in the metamorphic transition of the brain we generated a 3...

Both highand medium-pressure granulites have been found as because of the absence of modal minerals. The combination of petrographic textures, mineral compositions, metamorphic reaction enclaves and boudins in tonalitic–trondhjemitic–granodioritic gneisses in the Hengshan Complex. Petrological evidence from these history, petrogenetic grids and thermobarometric data defines a nearrocks indicate...

Metamorphic epitaxy technique offers the possibility of combining the advantages of low-cost and manufacturability of GaAs substrates and the high performance of InP-based devices. This paper will present the recent development of metamorphic HEMTs and HBTs and discuss their readiness for commercialization.