OBJECTIVE To test the hypothesis that regional left ventricular (LV) function during balloon angioplasty is related to the amount of collateral flow to the ischaemic region. DESIGN Prospective study. SETTING Tertiary referral centre. METHODS In 50 patients with coronary artery disease and without myocardial infarction, regional systolic and diastolic LV function was determined using tissu...

BACKGROUND Pregnancy in women with systemic lupus erythematosus (SLE) or antiphospholipid antibodies (APL Ab)--autoimmune conditions characterized by complement-mediated injury--is associated with increased risk of preeclampsia and miscarriage. Our previous studies in mice indicate that complement activation targeted to the placenta drives angiogenic imbalance and placental insufficiency. MET...

Recent Pwn2Own competitions have demonstrated the continued effectiveness of control hijacking attacks despite deployed countermeasures including stack canaries and ASLR. A powerful defense called Control flow Integrity (CFI) offers a principled approach to preventing such attacks. However, prior CFI implementations use static analysis and must limit protection to remain practical. These limita...

OBJECTIVE The pathogenesis of irritable bowel syndrome (IBS) is probably multifactorial with dysfunction at different levels of the brain-gut axis. The aim of this study was to evaluate an existing biobehavioral model of IBS symptom generation in a large group of patients. MATERIAL AND METHODS In 104 IBS patients, we assessed symptom severity by a symptom diary, visceral hypersensitivity usin...

Objective: To test the hypothesis that regional left ventricular (LV) function during balloon angioplasty is related to the amount of collateral flow to the ischaemic region. Design: Prospective study. Setting: Tertiary referral centre. Methods: In 50 patients with coronary artery disease and without myocardial infarction, regional systolic and diastolic LV function was determined using tissue ...

The effects of hexanoic extracts of Viscum cruciatum Sieber parasitic on Crataegus monogyna Jacq. (I), Crataegus monogyna Jacq. parasitized with Viscum cruciatum Sieber (II), and Crataegus monogyna Jacq. non-parasitized (III), and of a triterpenes enriched fractions isolated from I, II and III (CFI, CFII, CFIII respectively), on the growth of HEp-2 cells have been evaluated. All the samples dem...

In this article two studies are reported that tested the nature of the relationship between computer experience and computer anxiety. In the first study 184 first year psychology students were given a questionnaire that measured their computer experience in terms of e.g. breadth of experience, hours spent on working with computers, skills level, the nature of the first computer experience and t...

In typical software, many comparisons and subsequent branch operations are highly critical in terms of security. Examples include password checks, signature checks, secure boot, and user privilege checks. For embedded devices, these security-critical branches are a preferred target of fault attacks as a single bit flip or skipping a single instruction can lead to complete access to a system. In...

BACKGROUND Deletion of the complement factor H related 1 (CFHR1) gene is a consequence of non-allelic homologous recombination and has been reported to be more frequent in atypical haemolytic uraemic syndrome (aHUS) patients than in the normal population. Therefore, it is considered a susceptibility factor for the disease. aHUS is associated with hereditary or acquired abnormalities that lead t...

OBJECTIVE To determine whether myocardial contrast echocardiography can be used to quantify collateral derived myocardial flow in humans. METHODS In 25 patients undergoing coronary angioplasty, a collateral flow index (CFI) was determined using intracoronary wedge pressure distal to the stenosis to be dilated, with simultaneous mean aortic pressure measurements. During balloon occlusion, echo...