OBJECTIVES To identify combinations of tests and treatments to predict and prevent spontaneous preterm birth. DATA SOURCES Searches were run on the following databases up to September 2005 inclusive: MEDLINE, EMBASE, DARE, the Cochrane Library (CENTRAL and Cochrane Pregnancy and Childbirth Group trials register) and MEDION. We also contacted experts including the Cochrane Pregnancy and Childb...

The classification of human papillomavirus (HPV) intratypic lineages by complete genome sequencing is a determinant in understanding biological differences in association with this disease. In this work, we have characterised complete HPV genomes from southern Brazil. Fifteen cervicovaginal Pap smear negative samples previously categorised as HPV-positive were sequenced using ultradeep sequenci...

Abstract Background HSV2 increases HIV risk and is twice as common among women. We previously showed that cervicovaginal secretions exhibit innate anti-HSV2 activity was lower in adolescents women with HIV-- conditions associated vaginal dysbiosis increased HSV shedding. Our current study aims to test the hypothesis low anti-HSV explore molecules mechanisms contribute. Methods Cervicovaginal la...