PURPOSE Increasing risk of squamous cervical intraepithelial neoplasia (CIN) exits in HIV-infected women. However, the relatively low incidence of invasive carcinoma in the untreated HIV-infected population suggests an imbalance between cell proliferation and apoptosis. We investigated apoptosis and caspases in cervical samples from this population comparatively to non-HIV-infected and control ...

BACKGROUND USPIO is a contrast agent for MRI that can generate T2W images with low signal intensities. After subcutaneous or intravenous injection of USPIO, normal lymph node tissues uptake these nano-particles, but tumor cells do not. Thus, tumor metastasis can be detected using this contrast agent. OBJECTIVE The aim of this study was to access the feasibility of USPIO enhanced MRI for the d...

Survivin is an inhibitor of apoptosis protein (IAP) that is expressed in fetal development and in cancer. Survivin expression in premalignant lesions remains undefined. We obtained 73 samples of cervical squamous tissue, including 31 normal, 17 lowand 15 high-grade squamous intraepithelial lesions (LSILs, HSILs), and 10 squamous cell carcinomas (SCCs) from cone biopsy and hysterectomy specimens...

High-grade cervical dysplasia caused by human papillomavirus (HPV) type 16 is a lesion that should be susceptible to an HPV-specific immune response; disease initiation and persistence is predicated on expression of two viral Ags, E6 and E7. In immune-competent subjects, at least 25% of HPV16(+) high-grade cervical dysplasia lesions undergo complete regression. However, in the peripheral blood,...

Women with immunodeficiency conditions are a separate cohort of patients who need the close attention doctors and social workers. The aim study was to determine distribution CD68 CD3 immune cells in cervix women infectious non-infectious immunodeficiency, namely, HIV infection, chronic alcoholism their combination. Research groups were formed based on results autopsies 100 reproductive age, 25 ...

Background: Superficial mucocele presents as small, clear vesicle on noninflamed mucosa. In this study, we report several vesicles on the bucal mucosa of a woman diagnosed as superficial mucocele.Case Presentation: A 48-year old woman presented with multiple vesicles on her labial mucosa, ventral surface of the tongue, floor of the mouth and palate. A mucosal biopsy was taken from the vesicle. ...

Orificial tuberculosis has rarely been reported, especially in immunocompetent patients. It accounts for almost 2% of cases of cutaneous tuberculosis (1). The disease is characterized by one or more painful ulcerations involving mucous membranes and peri-orificial areas. CASE REPORT We report here the case of a 28-year-old Afro-Caucasian woman who presented with multiple ulcerations affecting b...