BACKGROUND Schistosomiasis and strongyloidiasis cause substantial morbidity and mortality among hundreds of millions of infected persons worldwide. In the United States, these infections are most commonly found among international travelers, immigrants, and refugees from areas of endemicity. Refugees resettled to the United States since 2000 include >3800 "Lost Boys and Girls" of Sudan and 8000...

Sir—Schwartz et al. [1] highlight hematospermia as a presenting symptom of schistosomiasis and comment that this presentation seems to be rare among travelers with schistosomiasis, although it is perhaps more common than is generally perceived. Indeed, several reports other than the 2 mentioned in their article have documented this presentation in returning travelers [2–4]. It is important to n...

INTRODUCTION Schistosomiasis mansoni is an endemic disease in underdeveloped or developing countries. The study aimed to define schistosomiasis prevalence in Bom Gosto village, Tutóia, Maranhão, in 2008 and detect intermediate host occurrence. METHODS A survey of data from stool samples examined by the Municipal Department of Health and National Health Foundation was conducted. Next, 60 snail...

Antibody response to Salmonella typhi O and H antigens was evaluated in 24 individuals with either hepatointestinal or hepatosplenic schistosomiasis mansoni before and after typhoid vaccination, and compared with that of non-infected controls. Before vaccination, Schistosoma-infected patients showed a higher frequency of positive antibody to O antigen and the same frequency to H antigen when co...

Schistosomiasis is currently estimated to infect about 200 million people World-wide, and 85% of them are believed to be in sub-Saharan Africa. It is ranked second to malaria in terms of extent of endemic areas and number of infected people. Several control options have been previously advocated, however, our better understanding of the epidemiology of the infection and disease, the advent of s...

This paper discusses central-local relations for healthcare policy in China from a principal-agent perspective, based on schistosomiasis control. In order to control the disease, the central government produced the Outline of the Mid-Long-Term National Plan for Schistosomiasis Prevention and Control (2004-2015) in 2004. By discussing the implementation of the National Outline at the provincial ...

Schistosomiasis is an endemic parasitic infection very linked to poverty. It is considered a world health problem since it infects people from 76 different countries especially tropical and subtropical regions. For many years, Morocco was endemic for shistosome infection. The unique form is urinary schistosomiasis and the first case was described in 1914. After an alarming prevalence rate (13 4...

The flatworm Schistosoma mansoni is a blood fluke parasite that causes schistosomiasis, a debilitating disease that occurs throughout the developing world. Current schistosomiasis control strategies are mainly based on chemotherapy, but many researchers believe that the best long-term strategy to control schistosomiasis is through immunization with an antischistosomiasis vaccine combined with d...

Macrophages play a key role in the pathogenesis of liver granuloma and fibrosis in schistosomiasis. However, the underlying mechanisms have not been fully characterized. This study revealed that the macrophages infiltrating the liver tissues in a murine model of Schistosoma japonica infection exhibited M2 functional polarization, and Notch1/Jagged1 signaling was significantly upregulated in the...

Schistosomiasis is a neglected parasitic tropical disease that claims around 200,000 human lives every year. Praziquantel (PZQ), the only drug recommended by the World Health Organization for the treatment and control of human schistosomiasis, is now facing the threat of drug resistance, indicating the urgent need for new effective compounds to treat this disease. Therefore, globally, there is ...