BACKGROUND To analyze voxel-wise correlation between cerebral blood flow (CBF) measured using ASL-MRI and cognition in patients with Alzheimer's disease (AD). METHODS Forty-one patients diagnosed with AD or mild cognitive impairment due to AD were recruited for this study. CBF images were obtained using ASL-MRI (n = 41) with a post-labeling delay (PLD) of 1.5 and 2.5 s (PLD1.5 and PLD2.5, res...

INTRODUCTION Use of electroconvulsive therapy (ECT) is limited by cognitive disturbance. Focal electrically-administered seizure therapy (FEAST) is designed to initiate focal seizures in the prefrontal cortex. To date, no studies have documented the effects of FEAST on regional cerebral blood flow (rCBF). METHODS A 72 year old depressed man underwent three single photon emission computed tomo...

anosmia following head trauma is relatively common and in many cases is persistent and irreversible. the ability to objectively measure such a decline in smelling, for both clinical and medicolegal goals, is very important. the aim of this study was to find results of brain single photon emission computed tomography (spect) in anosmic subjects after closed head trauma. this case-control cross s...

introduction: it is recommended that the physician apply at least a semi-quantitative segmental scoring system in myocardial perfusion spect.  we aimed to assess the agreement between automated semi-quantitative analysis using qps (quantitative perfusion spect) software and visual approach for calculation of summed stress  score (sss), summed rest score (srs) and summed difference score (sds). ...

this study evaluated the relationship between the location of the most severe coronary artery stenosis and the subsequent acute myocardial infarction (ami). methods: of 1590 patients who were admitted with a diagnosis of ami, we identified 44 patients who had undergone previous myocardial perfusion spect. thirty-one of these patients also had previous coronary angiography. the relationship betw...

discussion the reason is that we assess the relative and not absolute differences of the tracer uptake in this imaging modality. there may be other findings on mpi images which could help us overcome this pitfall, including detecting wall motion abnormalities, lung uptake of the tracer, or transient ischemic dilation. another important issue is the ecg changes during exercise stress testing, wh...

it is of value to determine the amount of viable myocardial tissue in patients suffering from chronic coronary artery disease and ventricular dysfunction. having the capability of evaluating both myocardial perfusion and function, simultaneously, myocardial scanning by ecg-gated is an appropriate method for this purpose. the aim of this study was to compare the results of myocardial perfusion a...

Left ventricular (LV) function and volumes, along with myocardial perfusion, have major diagnostic and prognostic importance inpatients with coronary artery disease [4,11,13,14, 18,20,27]. Myocardial perfusion scintigraphy is a well-established technique for evaluation of myocardial perfusion [16,26,37,38]. Electro cardiographic gating during the acquisition of SPECT perfusion images has become...

fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. to increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. in 46 patients (48.8%) fixed perfusion ...

UNLABELLED Myocardial perfusion imaging with SPECT (SPECT-MPI) and 64-slice CT angiography (CTA) are both established techniques for the noninvasive evaluation of coronary artery disease (CAD). Three-dimensional (3D) SPECT/CT image fusion may offer an incremental diagnostic value by integrating both sets of information. We report our first clinical experiences with fused 3D SPECT/CT in CAD pati...