background: nitric oxide synthase (nos) activity is increased during hypertension and cerebral ischemia. nos inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (bbb) disruption and cerebral edema formation during stroke in acute hypertension. here, we investigated the role of nos inhibition in progression of edema formation and bbb d...

Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...

to minimize the risk of embolic events, several protection strategies have been introduced. we have evaluated the short-term outcome of patients who underwent carotid stenting with the routine use of cerebral protection devices. in our center, 36 successful carotid stenting procedures (of 38 attempted) were performed in 37 patients (23 men; age mean [sd] 667 years). cerebral protection involv...

background: anticoagulation therapy is a routine treatment in patients with hemorrhagic cerebral venous thrombosis (cvt). however, fear of hemorrhagic complications and deterioration course following anticoagulation often disturbs the responsible physician. methods: this was a prospective observational study on consecutive cvt patients with hemorrhagic venous infarction or subarachnoid hemorrha...

conclusions the primary treatment for gh-producing adenoma is surgery; however, this patient has high surgical risk from her severe cardiomyopathy. radiotherapy poses a greater risk because of increased cerebrovascular mortality. somatostatin receptor ligands are significantly associated with improvement of cardiovascular and hemodynamic parameters. dopamine agonists must be considered regardle...

renal cell carcinoma comprises about 2% of adult tumors. the overall 10-year survival rate of patients with rcc after nephrectomy is about 18-27%. the incidence of metastasis of initial rcc is about 24-28%, but this rate after nephrectomy is as high as 51%. the most common site of recurrence is the lung, however liver and bone metastases are common. there are many reported cases with late metas...

the adhesive interaction between tumor cells and the host cells or the extracellular matrix plays a crucial role in tumor metastasis. to evaluate the mediation of cell adhesion by daphne mucronata, an anti-cancer medicinal plant in iranian folk medicine, the adhesion of thrombin activated human platelets to the cultured monocytes or hl-60 cells was investigated under the effect of the plant ext...

purpose: to report a case of metastatic tumor to the right upper eyelid originating from a lung adenocarcinoma without any systemic signs. case report: a 68-year-old man had a two-month history of painless swelling in the right upper eyelid. the tumor slowly grew. two years before his presentation, he had received chemotherapy for lung cancer for one year. systemic and ocular examinations were ...