Abstract Vaccine-induced thrombotic thrombocytopenia with cerebral venous thrombosis is a syndrome recently described in young adults within two weeks from the first dose of ChAdOx1 nCoV-19 vaccine. Here we report cases malignant middle artery (MCA) infarct and 9-10 days following vaccination. The arrived our facility around same time but different geographical areas, potentially excluding epid...

BACKGROUND AND PURPOSE Experimental stroke models are essential to study in vivo pathophysiological processes of focal cerebral ischemia. In this study, an embolic stroke model in rats was applied (1) to characterize early development of regional cerebral blood flow and metabolism with positron emission tomography (PET) using [(15)O]H(2)O and [(18)F]-2-fluoro-2-deoxy-D-glucose (FDG); and (2) to...

Fetal type posterior cerebral artery (FTPCA) is a variant of circulation brain, in which the distal part (PCA) perfused by branch internal carotid (ICA) via fetal communicating (fetal PCOM). In presence PCOM, paradoxical concurrent infarction anterior and may happen. We report 67-year-old man who presented with sudden onset right sided weakness aphasia, National Institutes Health Stroke Scale (...

A 39-year-old man presented with a pure motor stroke 9 days after cervical chiropractic manipulation. Computerised tomographic scanning showed a pontine infarct. Cerebral angiography showed changes consistent with the diagnosis of bilateral vertebral artery dissection. It is postulated that the infarct resulted from artery-to-artery embolism.

We assessed neurological outcomes, infarct volume, and the expression of nestin and caspase-3 in the hippocampal dentate gyrus following middle cerebral artery occlusion (MCAO) followed by reperfusion, with mild hypothermia (MH) treatment at the onset of ischemia in a MCAO rat model. Reperfusion began 2 hours after the MCAO model was set-up. MH treatment began at the onset of ischemia and was m...

a simple transfusion over erythrocytapheresis early in the course of ACS is lacking. To our knowledge, no randomized control trial exists comparing simple transfusion therapy with erythrocytapheresis for ACS. Further, the potential benefits versus risks of repeated simple transfusions in this patient population should be evaluated carefully. Of 5 patients, 4 had a positive fluid balance prior t...

Hypertension is involved in the exacerbation of stroke. It is unclear how blood-brain barrier (BBB) tight-junction (TJ) and ion transporter proteins critical for maintaining brain homeostasis contribute to cerebral infarction during hypertension development. In the present study, we investigated cerebral infarct volume following permanent 4-h middle cerebral artery occlusion (MCAO) and characte...

The Levine rat preparation, the gerbil stroke model, and appropriate control animals were used to determine if the 2,3,5-triphenyltetrazolium chloride (TTC) would selectively identify noninfarcted versus infarcted cerebral tissue. The TTC is frequently used to quantify infarcted myocardial tissue and has been shown to have great specificity, reproducibility, and efficacy. The TTC produces a red...

Stroke is the second leading cause of death and a major cause of morbidity and mortality in western as well as developing countries. Adiponectin is a fat-derived plasma protein that has beneficial actions on cerebrovascular disorders. A low level of plasma adiponectin is associated with increased mortality after ischemic stroke. Interleukin 6 is a cytokine, which is elevated in inflammatory, tr...