Embolic strokes of undetermined source comprise a subset of cryptogenic ischemic strokes. It is thought that some embolic strokes of undetermined source could be due to left atrial thromboembolism without atrial fibrillation. The authors sought to determine whether a marker of left atrial pathological changes could pose as a surrogate marker of nonarrhythmogenic atrial thromboembolism in emboli...

Embolic strokes of undetermined source comprise a subset of cryptogenic ischemic strokes. It is thought that some embolic strokes of undetermined source could be due to left atrial thromboembolism without atrial fibrillation. The authors sought to determine whether a marker of left atrial pathological changes could pose as a surrogate marker of nonarrhythmogenic atrial thromboembolism in emboli...

Embolic strokes of undetermined source comprise a subset of cryptogenic ischemic strokes. It is thought that some embolic strokes of undetermined source could be due to left atrial thromboembolism without atrial fibrillation. The authors sought to determine whether a marker of left atrial pathological changes could pose as a surrogate marker of nonarrhythmogenic atrial thromboembolism in emboli...

Embolic strokes of undetermined source comprise a subset of cryptogenic ischemic strokes. It is thought that some embolic strokes of undetermined source could be due to left atrial thromboembolism without atrial fibrillation. The authors sought to determine whether a marker of left atrial pathological changes could pose as a surrogate marker of nonarrhythmogenic atrial thromboembolism in emboli...

BACKGROUND AND PURPOSE Asymptomatic embolic signals (ES) detected using transcranial Doppler have been reported in patients with potential cerebral embolic sources. They may be useful in risk stratification and in assessing therapies. First, it is essential to show whether they predict stroke risk. METHODS A systematic review and meta-analysis was performed to determine the prognostic value o...

Background: Stroke is the third leading cause of invalidism and death in industrialized countries. There are conflicting reports about the effects of Angiotensin II on ischemia-reperfusion brain injuries and most data have come from chronic hypertensive rats. In this study, hypotensive and non-hypotensive doses of candesartan were used to investigate the effects of angiotensin II AT1 receptor b...

A 66-year-old man suffering from neurologic symptoms caused by acute embolic total occlusion of the left middle cerebral artery was treated successfully with balloon angioplasty, and an ipsilateral carotid stenosis subsequently was dilated with stenting. The patient's clinical outcome 30 days later was favorable. This therapeutic option may prove to be a useful means of treating a patient with ...

BACKGROUND AND PURPOSE Thrombolysis with tPA is the only FDA-approved therapy for acute ischemic stroke. But its widespread application remains limited by narrow treatment time windows and the related risks of cerebral hemorrhage. In this study, we ask whether minocycline can prevent tPA-associated cerebral hemorrhage and extend the reperfusion window in an experimental stroke model in rats. ...

Embolic strokes of undetermined source comprise a subset of cryptogenic ischemic strokes. It is thought that some embolic strokes of undetermined source could be due to left atrial thromboembolism without atrial fibrillation. The authors sought to determine whether a marker of left atrial pathological changes could pose as a surrogate marker of nonarrhythmogenic atrial thromboembolism in emboli...