Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of...

cadmium (cd), known as a non-essential heavy metal, can cause oxidative stress in plants. in this study, an attempt was carried out to find out whether cd-induced oxidative and microscopic changes could be observed in the early stage of seedling growth. seeds of brassica napus (cvs. zheda 619 and zs 758) were germinated in vitro at 0, 100, 200, 300, and 500 μm cd concentrations in dark for 48 h...

in this study, the milk-derived galactooligosaccharides (gos) were produced by lactobacillus delbrueckii subsp. bulgaricus and refined by an ultrafiltration-nanofiltration continuous membrane. by further investigation, we found that the gos product purified by gel permeation chromatography mainly contained low molecular weight disaccharide and trisaccharide, that is, 4-β-galactobiose and tri-ga...

background: numerous evidences indicate that in some hiv-1 positive patients, the humoral and cellular immune responses are induced against hiv-1 proteins and this is inversely related to the progress of infection. objective: the aim of this study was the evaluation of the adenovectors containing hiv genes in induction of immune responses in mice. methods: the hiv-1 genes including gag p24, rev...

parkinson’s disease (pd) is the second most common neurodegenerative brain disorder which is around 1.5 times more common in men than in women. currently, drug medications, surgery, and lifestyle changes are common approaches to pd, while all of them focused on reducing the symptoms. therefore, regenerative medicine based on stem cell (sc) therapies has raised a promising hope. various types of...

the eukaryotic complexity involves the expression and regulation of genes via rna-dna, rna-rna, dna-protein and rna-protein interactions. recently, the role of rna molecules in the regulation of genes in higher organisms has become more evident, especially with the discovery that about 97% of the transcriptional output in higher organisms are represented as noncoding rnas: rrna, snornas, trna, ...

fitzhugh-nagumo (fhn) model is a famous reaction-diffusion system which first introduced for the conduction of electrical impulses along a nerve fiber. this model is also considered as an abstract model for pattern formation. here, we have used the cellular automata method to simulate the pattern formation of the fhn model. it is shown that the pattern of this model is very similar to those of ...

urban settlements and their connectivity will be the dominant driver of global change during the twenty-first century. in an attempt to assess the effects of urban growth on available land for other uses and its associated impacts on environmental parameters, we modeled the change in the extent of gorgan city, the capital of the golestan province of iran. we used landsat tm and etm+ imagery of ...

abstract this paper presents a multiobjective power control algorithm that updates the transmitted power based on local information. the proposed algorithm is expanded by using multiobjective optimization schemes. the objectives to be optimized in this paper are determined so as to reduce the sinr fluctuations as well as maintaining the sinr to an acceptable level with minimizing an average tra...