Values are motivational constructs that determine what is important to us and which goals we choose to pursue. Cross-cultural research suggests that the structure of the human value system is universal, but people and cultures differ in terms of relative value priorities. Differences in psychological value hierarchies can be parsimoniously described using the orthogonal dimensions self-interest...

The aim of this research was to investigate the glutathione system components and their association with polymorphisms GST genes in men with infertility. Materials and Methods: One hundred and sixty Russian men of reproductive age (Caucasians) who came to the public health institution Republican Perinatal Center in Ulan-Ude with an infertility problem of one year and more after marriage were in...

We report on the role of conserved stress-response pathways for cellular tolerance to a pore forming toxin. First, we observed that small molecular weight inhibitors including of eIF2α-phosphatase, jun-N-terminal kinase (JNK), and PI3-kinase sensitized normal mouse embryonal fibroblasts (MEFs) to the small pore forming S. aureus α-toxin. Sensitization depended on expression of mADAM10, the muri...

BACKGROUND Previous studies have revealed significant differences between populations for genotypic frequencies of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) polymorphisms. In order to find the frequency of the null genotypes of GSTM1 and GSTT1 in Iranian populations, the present study was carried out. METHODS The total study subjects consisted of 1340 unrelated healthy Muslims/Irani...

Glutathione S-transferase T1 (GSTT1) null genotype has been indicated to be correlated with preterm delivery (PTD) susceptibility, but study results were still debatable. Thus, a meta-analysis was conducted. PubMed, EMBASE, and CNKI were searched. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to calculate the strength of association in the random-effects model or fixed-effects...

By directly recording electrical activity from the human brain, neuroscientists at the School of Medicine have shown that distinct, distant groups of brain areas that support memory retrieval act in concert, even during sleep. The findings, described in a study published online April 8 in Neuron, confirm for the first time that specific electrical patterns of coordinated neural activity in wide...

Dihydrogen sulfide recently emerged as a biological signaling molecule with important physiological roles and significant pharmacological potential. Chemically plausible explanations for its mechanisms of action have remained elusive, however. Here, we report that H(2)S reacts with S-nitrosothiols to form thionitrous acid (HSNO), the smallest S-nitrosothiol. These results demonstrate that, at t...

The mu and theta classes of glutathione S-transferases (GST) may affect the development of cutaneous malignant melanoma (CMM) by decreasing cellular oxidative stress in skin. These isozymes are absent in a large proportion of the population because of germ-line homozygous deletions in the genes encoding GSTM1 and GSTT1. To determine the association between GSTM1 and GSTT1 homozygous deletions (...

S-Box is the only non-linear component in Advanced Encryption Standard(AES) which determine its strength. The Look-Up Table based S-Box of conventional AES occupies large storage space, reduced throughput and consumes more power. This article presents the design of an S-Box based on Reversible Cellular Automata function that reduces the implementation cost. Further, Cellular Automata functions ...