Spinal cord injury (SCI) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. To date, there is no definite treatment for repairing damaged spinal cord tissue. In this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, Schwann cells,...

Fasting, that is usually described as abstinence from all food and drink for a period of time, has been experienced for ages. Health, protest, religious expressions of devotion and purification are the most important reasons for fasting. Many changes occur in the body during fasting including metabolic, mineral, hormonal, immunological and psychological. Its use as one of the oldest therapies a...

Ovarian cancer (OC) is associated with a dismal prognosis and lack of curative treatment. Increased understanding OC biology has led to the development several targeted therapies, including antiangiogenic agents poly(ADP-ribose) polymerase (PARP) inhibitors. Cell cycle inhibitors endocrine therapy such as selective estrogen receptor down regulators are currently under development. In this artic...

Natural killer (NK) cells are a gatekeeper of the body’s innate defense system against cancers and infections. A growing body literature from us others finds that NK promote anti-cancer immune surveillance, defects in cell development associated with poor clinical prognosis cancers. In preclinical studies, were found to drive tumor regression delay relapse. Because potentially less damaging eas...

Neurodegenerative diseases are the hereditary and sporadic diseases which are characterized by progressive neuronal loss of the nervous system and are emerging as the leading cause of death, disabilities, and a socioeconomic burden due to an increase in life expectancy. There are many neurodegenerative diseases including Alzheimer’s disease, Parkinson’s, disease, amyotrophic lateral...

Cell-gene therapy is a dynamic constituent of novel medical biotechnology. Neurodegenerative disordersin which damage to or demise of specific brain cell types plays central role, are clear examples of diseasecandidate for cell replacement therapy. Dopaminergic (DAergic) neurons biosynthesize dopamine, a vitalneurotransmitter in the central nervous system. Due to the involveme...

background: multiple sclerosis (ms) is an unpredictable neurological disease leading to severe disability in young adults.  the  majority of ms patients  use  complementary and     alternative medicine  (cam)  as adjunct  to conventional  therapies.  this study  aimed  to  investigate the prevalence  of cam utilization among  iranian patients with ms and their attitude  toward the cam usage. me...