One of the regulated forms cell death is cell-in-cell (CIC) structure, in which a surviving engulfed by another cell, mechanism that causes an adjacent cell. Several investigators have previously shown presence CICs independent risk factor significantly associated with decreased survival patients various types cancer. In this review, we summarize role CIC tumor microenvironment (TME), including...

lithium disilicate nano-powders were synthesized via a mild condition hydrothermal reaction at 180 ºc for 48 and 72 h with a non stoichiometric1:2 li:si molar ratio in naoh aqueous solution using li2co3 and sio2.h2o as raw materials. the synthesized materials were characterized by powder x-ray diffraction (pxrd) technique and fourier transform infrared (ftir) spectroscopy. the xrd data showed t...

objective: biomaterial technology, when combined with emerging human induced pluripotent stem cell (hipsc) technology, provides a promising strategy for patient-specific tissue engineering. in this study, we have evaluated the physical effects of collagen scaffolds fabricated at various freezing temperatures on the behavior of hipsc-derived neural progenitors (hipsc-nps). in addition, the coati...

background: there is evidence that mesangial cell structural changes contribute to the pathogenesis of diabetic nephropathy. to gain better insight into the mechanisms responsible for this issue, present study focused on effect of cord blood mononuclear cells (mncs) derived cd133 positive cells on mesangial cell structure and function. materials and methods: the animals were randomly divided in...