Gastrulation generates three layers of cells (ectoderm, mesoderm, endoderm) from a single sheet, while large scale cell movements occur across the entire embryo. In amniote (reptiles, birds, mammals) embryos, the deep layers arise by epithelial-to-mesenchymal transition (EMT) at a morphologically stable midline structure, the primitive streak (PS). We know very little about how these events are...

Many in situ spacecraft observations have demonstrated that magnetic reconnection the Earth's magnetotail is largely controlled by pre-reconnection current sheet configuration. One of most important thin characteristics preponderance electron currents driven strong polarized electric fields, which are commonly observed well before reconnection. We use particle-in-cell simulations to investigate...

The endoplasmic reticulum (ER) is both structurally and functionally complex, consisting of a dynamic network of interconnected sheets and tubules. To achieve a more comprehensive view of ER organization in interphase and mitotic cells and to address a discrepancy in the field (i.e., whether ER sheets persist, or are transformed to tubules, during mitosis), we analyzed the ER in four different ...

Quantum cellular automata (QCA) is an innovative approach that incorporates quantum entities in classical computation processes. Binary information is encoded in different charge states of the QCA cells and transmitted by the inter-cell Coulomb interaction. Despite the promise of QCA, however, it remains a challenge to identify suitable building blocks for the construction of QCA. Graphene has ...

Understanding cell morphogenesis during metazoan development requires knowledge of how cells and the extracellular matrix produce and respond to forces. We investigated how apoptosis, which remodels tissue by eliminating supernumerary cells, also contributes forces to a tissue (the amnioserosa) that promotes cell-sheet fusion (dorsal closure) in the Drosophila embryo. We showed that expression ...

Cells move along surfaces both as single cells and multi-cellular units. Recent research points toward pivotal roles for water flux through aquaporins (AQPs) in single cell migration. Their expression is known to facilitate this process by promoting rapid shape changes. However, little is known about the impact on migrating epithelial sheets during wound healing and epithelial renewal. Here, we...

In order to understand organizational memory, it is important to understand how things become adopted as memory resources in organizations. In this paper, we describe the genesis and use of an artifact that became a memory resource for a wide range of activities. We discuss how the creation and use of the rush cheat sheet (RCS) and its associated representations at Dallas Ft. Worth TRACON broug...

Reading the medical literature requires some sophistication. This scoring sheet points out some important issues to consider when reading medical papers. Considerations raised herein are not to be taken as absolute, but instead as strong guidelines. Furthermore, this scoring sheet can be used in preparing manuscripts as it is a valuable “checksheet” to ensure all bases are covered. The more poi...

this information sheet contains the necessary information to educate mothers in the early weeks after delivery. so in a relaxed opportunity to read it. if you plan to feed your baby by breast feeding, it is necessary to read it prior to discharge from hospital. note that the duration of breast feeding in the first weeks after the labor is 20 minutes. the best way for breastfeeding is to give th...

An approximation method of Moore for Kelvin-Helmholtz instability is formulated as a general method for two-dimensional, incompressible, inviscid flows generated by a vortex sheet. In this method the nonlocal equations describing evolution of the sheet are approximated by a system of (local) differential equations. These equations are useful for predicting singularity formation on the sheet and...