background: for xenograft models of triple-negative breast cancer (tnbc) to be valuable in development of molecularly-targeted drugs, careful characterization is essential to their validation. the present study aimed to validate the tnbc xenograft model with a specific focus on angiogenesis. methods : twelve tnbc xenograft tumors and 12 human breast cancer tumors (htnbc) were included in this s...

objective(s): many cancer cells show significant resistance to drugs that kill drug sensitive cancer cells and non-tumor cells and such resistance might be a consequence of the difference in metabolism. therefore, studying the metabolism of drug resistant cancer cells and comparison with drug sensitive and normal cell lines is the objective of this research. material and methods:metabolism of c...

garlic and onions as dietary constituents and medicines have been used for many disorders which dates back to the early civilization. it has been shown that different species of allium have immunomodulating effects. in this study, we sought to determine if methanolic and chloroformic extracts of allim fistulosum l. (leek) have any effect on cell-mediated immune response in mice. methanolic and ...

operational variables of a mineral processing circuit are subjected to different variations. steady-statesimulation of processes provides an estimate of their ideal stable performance whereas their dynamicsimulation predicts the effects of the variations on the processes or their subsequent processes. in thispaper, a dynamic simulator containing some of the major equipment of mineral processing...

Breast cancer tissues include carcinoma cells and stromal cells, intra-tumoral stroma that consists of different types cells. For this point, cell-cell interaction communication have a potential role in progression. Mono-cell culture is used for treatment approaches. However, can not be evaluated on mono-culture So, co-culture models provide low-cost screening to determine cell proliferation dr...