• The thermal management strategies of PEMFC are reviewed. waste heat recovery pathways presented. challenges and prospects the aforementioned areas discussed. Despite that Proton Exchange Membrane Fuel Cell (PEMFC) is considered to be an efficient power device; around half energy produced from electrochemical reaction dissipated as due irreversibility cathodic reaction, Ohmic resistance, mass ...

Guanidinium-rich molecules, such as cell-penetrating peptides, efficiently enter living cells in a non-endocytic energy-independent manner and transport a wide range of cargos, including drugs and biomarkers. The mechanism by which these highly cationic molecules efficiently cross the hydrophobic barrier imposed by the plasma membrane remains a fundamental open question. Here, a combination of ...

Patch-clamp technique is the gold standard for cellular electrophysiological measurements, which capable of measuring single ion transport events across cell membrane. However, measurement possesses significant complexities, and it requires a high level expertise, while its experimental throughput nevertheless considerably low. Here, we suggest experimentally demonstrate laser-assisted method p...

Gram-negative bacteria have an outer membrane that serves as a barrier to noxious agents in the environment. This protective function is dependent on lipopolysaccharide, a large glycolipid located in the outer leaflet of the outer membrane. Lipopolysaccharide is synthesized at the cytoplasmic membrane and must be transported to the cell surface. To understand this transport process, we reconsti...

The bidirectional transport of calcium in rat liver was studied using slices labeled with Ca(47) in a closed two compartment system. Steady-state conditions were observed with influx and efflux transfer coefficients of 0.070 and 0.018 per minute, respectively. The rapidly exchanging cell fraction of calcium existed at a concentration three times higher than the average cell concentration of cal...

introduction perforation of maxillary sinus mucous membrane is of the most prevalent complication during open sinus lift surgery. moreover, such complication can usually be managed by an absorbable membrane. as far as absorbable membranes are concerned, decellularized maxillary sinus mucous membranes, which is an extracellular matrix, can be used as a biologic scaffold and insulating membrane i...

Drug-induced cholestasis is the main type of liver disorder accompanied by high morbidity and mortality. Evidence for the role of hepatobiliary pumps in the cholestasis patho-mechanism is constantly increasing. Recognition of the interactions of chemical agents with these transporters at the initial phases of drug discovery can help develop new drug candidates with low cholestasis potential. Th...

Every polypeptide has a specific function as well as a unique functional location, i.e. an intraor extra-cellular location where it fulfils its function. There are two facts which turned the latter into a central problem in our understanding of gene expression in both the prokaryotic and the eukaryotic cell: (i) there is one site of protein synthesis, the cytoplasm, but there are many different...

In this article, one-phase and three dimensional computational fluid dynamics analysis was utilized to investigate the effect of annular field pattern of proton exchange membrane fuel cells (PEMFC) with different geometry on the performances and species distribution. This computational fluid dynamics code is used for solving the equation in single domain namely the flow field, the mass conserva...

       Gel dosage forms are successfully used as drug delivery systems considering their ability to control drug release and to protect medicaments from a hostile environment. The aim of this work was to investigate the properties of carbopol 934P polymeric system in water-misible cosolvents such as glycerin and alcohol. Benzocaine is a local anesthetic and the mucosal gel formulation is appl...