INTRODUCTION Increased bleeding is the most common cause of intrauterine device (IUD) removal. The use of alternative therapies to treat bleeding has increased due to the complications of medications. But most alternative therapies are not accepted by women. Therefore, conducting studies to find the right treatment with fewer complications and being acceptable is necessary. This study aimed to ...

Eight botanical preparations that are commonly used for the treatment of menopausal symptoms were tested for estrogenic activity. Methanol extracts of red clover (Trifolium pratense L.), chasteberry (Vitex agnus-castus L.), and hops (Humulus lupulus L.) showed significant competitive binding to estrogen receptors alpha (ER alpha) and beta (ER beta). With cultured Ishikawa (endometrial) cells, r...

Objective(s) There is well documented evidence for the increase in widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within the populations. In the present study, we investigated the influence of Vitex agnus-castus (vitex) on anxiety-like behaviors of rats. Materials and Methods Elevated plus maze which is one of the ...

Background: Plant materials continue to play an important role in the maintenance of human health since antiquity. Phytoestrogens are naturally occurring plant substances that can either mimic or antagonize the action of endogenous estrogens. This study was conducted to investigate the effects of vitex agnus as a phytoestrogenic plants, essential oil on structure and morphology of seminiferous ...

In the twentieth century, a whole teaching of mastopathy was formed. However, over time, accumulated data have questioned existence as separate nosological form, because term “fibrocystic disease” while mastalgia is most common symptom does not correspond to holistic concept disease. This “disease” can be diagnosed in any woman and more or less successfully treated. United States, this obsolete...

Although Vitex megapotamica (Spreng.) Moldenke is used in Brazilian folk medicine as hypolipidemic drug no study has been conducted to evaluate the effects of this species in an experimental model of atherosclerosis. So, the aim of this study was to evaluate the possible renoprotective activity of methanolic extract obtained from Vitex megapotamica (MEVM) using C57BL/6 LDLr-null mice submitted ...