Over the past 20 years, the use of Computer Algebra Systems (CAS) has helped with the teaching of mathematics in engineering schools. However the traditional use of CAS only in math labs has led to a narrow view by the student: the CAS is an additional work, not included in the learning process. The didactic guidelines of the European Higher Education Area (EHEA) propose a new teaching-learning...

A Complex Adaptive System (CAS) is a network of selforganizing, intelligent agents that share knowledge and adapt their operations in order to achieve overall system goals. Three things are needed to understand, design, and evaluate CAS. First, a mathematical model or way-ofthinking about CAS, called Context-Sensitive Systems (CSS) theory, is required to provide a solid foundation upon which to...

The Multinational Enterprise (MNE) is recognized as a Complex Adaptive System (CAS). General characteristics of a CAS are identified and explored as to their particular relevance to organizational processes associated with MNEs. The exploration suggests useful insights into the macro behavior of MNEs. Analysis supports CAS research as a potentially valuable model in understanding the macro proc...

Abstract Nous décrivons un cas d'ectopia cordis, une malformation cardiaque congénitale extrêmement rare dans laquelle le coeur est partiellement ou complètement situé en dehors des limites de la cage thoracique. Dans le cas que nous décrivons, elle est thoracique et isolée. Ce cas a été diagnostiqué en salle de naissance au Katanga, au sud de la République Démocratique du Congo. Il s'agit du p...

Using the hyperthermophile Pyrococcus furiosus, we have delineated several key steps in CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) invader defence pathways. P. furiosus has seven transcriptionally active CRISPR loci that together encode a total of 200 crRNAs (CRISPR RNAs). The 27 Cas proteins in this organism represent three distinct pathways and ...

The physico-chemical and interfacial properties of fat emulsions influence lipid digestion and may affect postprandial responses. The aim of the present study was to determine the effects of the modification of the interfacial layer of a fat emulsion by cross-linking on postprandial metabolic and appetite responses. A total of fifteen healthy individuals (26.5 (sem 6.9) years and BMI 21.9 (sem ...

BACKGROUND Airway smooth muscle contraction is critical for maintenance of appropriate airway tone, and has been implicated in asthma pathogenesis. Smooth muscle contraction requires an "engine" (myosin activation) and a "transmission system" (actin cytoskeletal remodeling). However, the mechanisms that control actin remodeling in smooth muscle are not fully elucidated. The adapter protein Crk-...

Cellular automata (CAs) are dynamic frameworks which exhibit complex global behavior from simple local interaction and computation. Since the inception of CA by von Neumann in 1950s, it has attracted the attention of several researchers over various backgrounds and fields for modeling different physical, natural as well as real-life phenomena. Classically, CAs are uniform. However, non-uniformi...