نتایج جستجو برای: cardiotoxicity
تعداد نتایج: 5220 فیلتر نتایج به سال:
BACKGROUND Because cancer patients survive longer, the impact of cardiotoxicity associated with the use of cancer treatments escalates. The present study investigates whether early alterations of myocardial strain and blood biomarkers predict incident cardiotoxicity in patients with breast cancer during treatment with anthracyclines, taxanes, and trastuzumab. METHODS AND RESULTS Eighty-one wo...
Buchanania axillaries(Anacardiaceae) is a traditional herbal medicine , the leaves are used to treat many diseases including cardiotoxicity.’The present study was designed to scientifically evaluate the cardioprotective potential of the ethanol extract of Buchanania axillaries(BA), on Doxorubicin (DOX) induced cardiotoxicity, in albino rats. DOX is one of the most effective chemotherapeutic dru...
Doxorubicin is among the essential medicines with a wide antitumor spectrum, but its clinical application is limited by its cardiotoxicity. We recently discovered that ROCK1 is a key molecule in mediating cardiac remodeling in response to various stresses. To determine the roles of ROCK1 in doxorubicin cardiotoxicity, we gave three doses of doxorubicin injections to wild type (WT) and ROCK1-/- ...
BACKGROUND Various trials have compared the efficacy and toxicity of liposomal doxorubicin-based chemotherapy with the conventional formulation of doxorubicin although arriving at inconsistent conclusions. To derive a conclusive assessment of the efficacy and cardiotoxicity associated with chemotherapy, we performed a meta-analysis by combining data from all eligible randomized controlled trial...
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