نتایج جستجو برای: cardiolipin
تعداد نتایج: 2259 فیلتر نتایج به سال:
Phthalocyanine (Pc) 4, like many photosensitizers for photodynamic therapy (PDT), localizes to intracellular membranes, especially mitochondria. Pc 4-PDT photodamages Bcl-2 and Bcl-xL, antiapoptotic proteins interacting with the permeability transition pore complex that forms at contact sites between the inner and outer mitochondrial membranes. These complexes and the inner membrane are unique ...
Tafazzin is a conserved mitochondrial protein that is required to maintain normal content and composition of cardiolipin. We used electron tomography to investigate the effect of tafazzin deletion on mitochondrial structure and found that cellular differentiation plays a crucial role in the manifestation of abnormalities. This conclusion was reached by comparing differentiated cardiomyocytes wi...
I. Phospholipds were studied in the heart muscles, skeletal muscles and livers of scven Ayrshire calves which received vitamin E-free maize 011 (in filled milk) VTith and without supplementary a-tocopherol from I week old for 17 d. The calves that were not given vitamin F: developed muscular dystrophy. 2. Decreased amounts of cardiolipin and increased amounts of sphlngomyelin were found in the ...
Phosphatidylglycerol is found in almost all bacterial types. For example, Escherichia coli, a widely studied organism, has up to 20% of phosphatidylglycerol in its membranes (phosphatidylethanolamine makes up much of the rest with a little cardiolipin). In many bacteria, the diacyl form of the lipid predominates, but in others the alkylacyland alkenylacyl forms are more abundant. Phosphatidylgl...
Tim23 mediates protein translocation into mitochondria. Although inserted into the inner membrane, the dynamic association of its intermembrane space (IMS) domain with the outer membrane promotes protein import. However, little is known about the molecular basis of this interaction. Here, we demonstrate that the IMS domain of Tim23 tightly associates with both inner and outer mitochondrial memb...
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