Pharmacologic therapy for hypertension is effective for the majo rity of patients with hypertension, but there remains a subset of the population with treatment resistant hypertension who cannot achieve their blood pressure (BP) goal despite multiple medications. For these patients at increased risk of cardio vascular disease and end-organ damage, additional therapies need to be considered. Thi...

Popular belief has it that alcohol, particularly red wine, protects against atherosclerosis and associated cardio- and cerebrovascular conditions. That presumption motivates this paper, which describes the mechanisms underlying the J-shaped risk curve for alcohol use, with benefits for vascular disease risk at low consumption levels and harmful effects--both directly on the user and indirectly ...

conclusion peripheral arterial calcification is significantly correlated with cad extent in patients with pad. peripheral arterial calcification can be a useful marker for predicting multivessel-cad. results lecs in multivessel-cad were significantly higher than those in nonsignificant cad (10.0 ± 5.8 versus 4.0 ± 3.1, p < 0.001). lecs significantly correlated with ccs (r = 0.831, p < 0.001) an...

Background: Glyceryl Trinitrate (GTN) is a potent smooth muscle relaxant and vasodilator. There are conflicting reports regarding its efficacy as a bronchodilator. The aim of this study was to examine the effect of nebulized GTN on airway calibare and cardio vascular system in normal subjects. Methods: We studied 24 normal subjects (6 female) on two occasions, administering either nebulized GTN...

The cardiorenal syndrome includes the widely known relationship between kidney function and cardiovascular disease. A large number of patients have various degrees of heart and kidney dysfunction worldwide, both in developed and developing countries. Disorders affecting one of them mostly involve the other. Such interactions represent the pathogenesis for a clinical condition called cardiorenal...