OBJECTIVE To describe a patient with unilateral diaphragmatic paralysis due to multiple myeloma (MM) involving the cervical spine and related structures. CASE PRESENTATION AND INTERVENTION A 52-year-old female presented with dyspnea, low back and widespread bone pain. She was diagnosed as having MM with vertebral involvement and unilateral paralysis of the diaphragm. She received two cycles o...

U NILATERAL diaphragm paralysis after interscalene nerve block can result in respiratory disturbances that may have a substantial impact on quality of life and increased prevalence of respiratory infections. Several reports have estimated the incidence of transient diaphragm paralysis after routine interscalene blocks for shoulder surgery to be 100%, 3 however, with modified local anesthetic do...

Two procedures were used to estimate the relative contribution of neurotransmission failure (NF) to fatigue of the rat diaphragm at different rates of phrenic nerve stimulation. In one, direct muscle stimulation was intermittently superimposed on neural stimulation of the diaphragm, and the relative contribution of NF was estimated by the difference in generated tension. In a second procedure, ...

Respiratory muscle-associated stretch has been implicated in normal lung development (fetal breathing movements) and postpneumonectomy lung growth. To test the hypothesis that mechanical stretch from diaphragmatic contraction contributes to lung growth, we performed left phrenic nerve transections (PNT) in mice with and without ipsilateral pneumonectomy. PNT was demonstrated by asymmetric costa...

The electrical activity of intact branches of the phrenic nerve was studied during spontaneous respiration in the anaesthetized or decerebrate cat. The action potentials were displayed with opposite polarity according to whether their activity was of afferent or efferent origin. The afferent volleys could be grouped according to three modalities. The first group had a clear silent period during...

BACKGROUND In the investigation of patients with myasthenia gravis, repetitive supramaximal stimulation of an affected peripheral nerve is commonly performed to detect abnormal transmission at the neuromuscular junction. A study was undertaken to determine whether abnormal transmission could similarly be detected during stimulation of the phrenic nerves. METHODS The phrenic nerves were stimul...

objectives: the aim of this study was to evaluate the surgical approach in post traumatic diaphragmatic hernia. methods: this prospective cross-sectional study was conducted in the department of cardiovascular and thoracic surgery, sher-i- kashmir institute of medical sciences (skims), kashmir, india. we included all patients with post traumatic diaphragmatic hernia undergoing operation in our ...

cinoma for surgical treatment the physician must satisfy himself that the patient has sufficient pulmonary reserve and cardiac vascular reserve to withstand pneumonectomy should that be necessary. He must be certain there are no metastases. He must satisfy himself that the phrenic nerves, the sympathetic nerves, and the recurrent laryngeal nerves are not involved. He must, by examining the bari...

The more frequent diagnosis of sliding hiatal hernia has focused surgical attention on the crural fibres of the diaphragm. The part played by the muscular hiatus in " the closing mechanism " between stomach and oesophagus is, however, still undecided. Various experimental methods of dividing crural muscle and phrenic nerve have been tried at different centres to evaluate the importance of the m...

In a previous work we started the study of the influences of different methods of collapse-therapy-and particularly pneumothorax-on the respiratory function of each lung. We are presenting here the results of the air content analysis of each lung before and after the surgical paralysis of the phrenic nerve. Oianotti and Ceruti2 have seen in tracheotomized dogs that the ventilation of the lungs ...