Clam samples of Liochoncha ornata were collected for a period of one year from July 2009 to June 2010 at monthly interval. The soft tissue of clams was analyzed to detect some potentially toxic metals and polycyclic aromatic hydrocarbons (PAHs). Accumulation of Hg, Cd and Pb in the clam tissues showed variability with a mean concentration of 0.011±0.009, 1.769±0.942 and 0.015±0.039 μg/g wet wei...

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants; a number are carcinogenic. Metabolic polymorphisms may modulate susceptibility to PAH-induced DNA damage and carcinogenesis. This study investigates the relationship between PAH-DNA adduct levels (in maternal and newborn WBCs) and two polymorphisms: (a) an MspI RFLP in the 3' noncoding region of cytochrome P4501A1 ...

The relationship between intrauterine growth retardation (IUGR) and exposure to particulate matter [less than/equal to] 10 microm (PM(10)) and particulate matter [less than and equal to] 2.5 microm (PM(2.5))( )in early pregnancy was recently studied in the highly polluted district of Teplice (Northern Bohemia). From this observation rose the question about the possible role of the carcinogenic ...

The mammalian CYP1A1, CYP1A2, and CYP1B1 genes (encoding cytochromes P450 1A1, 1A2, and 1B1, respectively) are regulated by the aromatic hydrocarbon receptor (AHR). The CYP1 enzymes are responsible for both metabolically activating and detoxifying numerous polycyclic aromatic hydrocarbons (PAHs) and aromatic amines present in combustion products. Many substrates for CYP1 enzymes are AHR ligands...

Polycyclic aromatic hydrocarbons (PAHs) are the byproducts of the incomplete combustion of carbon-based fuels, and have high affinity towards DNA strands, ultimately exerting their carcinogenic effects. They are ubiquitousenvironmental contaminants,and can accumulate on tissues due to their lipophilic nature. In this article, we describe a novel concept for PAH removal from aqueous solutions us...

The reliability of using diagnostic binary ratios of particulate carcinogenic polycyclic aromatic hydrocarbons (PAHs) as chemical tracers for source characterisation was assessed by collecting PM10 samples from various air quality observatory sites in Thailand. The major objectives of this research were to evaluate the effects of day and night on the alterations of six different PAH diagnostic ...

Tobacco-smoke is associated with 75-90% of LC cases and ~50% occurs in developing countries (Parkin, et al. 2005; Parkin, et al. 1994). Several studies have demonstrated that organic and inorganic compounds are related with the development of cancer, including LC (Bradley and Golden 2006; De Palma, et al. 2008; Stavrides 2006). The association between cigarette smoking and various types of resp...

Exposure to polycyclic aromatic hydrocarbons (PAHs) in foundry workers has been evaluated by determination of benzo(a)pyrene-serum albumin adducts and urinary 1-hydroxypyrene. Benzo(a)pyrene binding to albumin and 1-hydroxypyrene were quantitatively measured by enzyme linked immunosorbent assay (ELISA) and reverse phase high performance liquid chromatography (HPLC), respectively. 70 male foundr...

Polycyclic aromatic hydrocarbons (PAHs) are a group of highly toxic organic pollutants. At present, there has only been limited research into PAH contamination in Tangxun Lake and Dong Lake, which the first second largest urban inland lakes China, respectively. This study investigated concentration, spatial distribution, sources, ecological risks PAHs water from Lake. The focus this is to use m...

Airborne fine particulate matter (PM2.5) pollution is known to have adverse effects on human health, and owing their carcinogenic mutagenic nature, polycyclic aromatic hydrocarbons (PAHs) are of particular concern. This study investigated the effect ultraviolet (UV)-induced photocatalysis degradation PAHs in PM2.5, employing titanium dioxide (TiO2)-supporting quartz fibre filters. A TiO2 layer ...