Supercritical carbon dioxide (SC-CO2) was used as solvent to synthesize oleyl oleate as an analog of Jojoba oil from oleic acid and oleyl alcohol with high conversion (100%) of the acid into ester in a short time of 100 min. Utilizing a low cost solid catalyst, p-toluenesulfonic acid monohydrate (PTSA), the esterification reaction was performed, without any prior preparation step...

Polycyclic aromatic hydrocarbons (PAHs) contaminants have toxic, carcinogenic, and mutagenic properties. Screening bacteria from different sources capable of carrying out the biodegradation is essential for mapping mobilization purposes applying them to polluted hydrocarbon environments. The study aims compare capacity PAH by two types isolated sources. method applied interaction between bacter...

We discovered on the chromosome of Saccharomyces cerevisiae Sigma 1278b novel genes involved in L-proline analogue L-azetidine-2-carboxylic acid resistance which are not present in the standard laboratory strains. The 5.4 kb-DNA fragment was cloned from the genomic library of the L-azetidine-2-carboxylic acid-resistant mutant derived from a cross between S. cerevisiae strains S288C and Sigma 12...

Single carbon to 18 carbon n-aliphatic carboxylic acids were tested for their attractive effects on female Aedes aegypti in a Y-tube olfactometer. Each acid was tested over a wide range of concentrations together with L-(+)-lactic acid, the indispensable synergist for other attractive components emitted from human hosts. The attractiveness of lactic acid was significantly augmented when combine...

Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylic acid 3 is prepared by PPA-catalyzed thermal lactamization of the respective 8-amino-7-[(2-carboxyethyl)thio]-1,4-dihydroquinoline-3-carboxylic acid 9. The latter synthon is obtained by reduction of the 8-nitro-1,4-dihydroquinoline precursor 8 which, in turn, is made accessible via interaction of 3-mercaptopropionic acid with 7-chloro-1-cyclo...

Some new biphenyl-4-carboxylic acid 5-(arylidene)-2-(aryl)-4-oxothiazolidin-3-yl amides have been synthesized and evaluated for anti-inflammatory activity. Biphenyl-4-carboxylic acid hydrazide was converted to the corresponding aryl hydrazones using aryl aldehydes in the presence of catalytic amount of glacial acetic acid. The aryl hydrazones on reaction with thioglycolic acid in the presence o...

Abstract This invited Team Profile was created by Shuo Wang, Igor Larrosa, Hideki Yorimitsu and Greg Perry. They recently published an article on carboxylic acid salts as dual-function reagents for carboxylation carbon isotope labeling. project brought together researchers based in Japan the UK, demonstrates how scientists with different cultural backgrounds can work to build powerful results. ...

Characterization of the circulating metabolites for a new chemical entity in humans is essential for safety assessment, an understanding of their contributions to pharmacologic activities, and their potential involvement in drug-drug interactions. This review examines the abundance of metabolites relative to the total parent drug [metabolite-to-parent (M/P) ratio] from 125 drugs in relation to ...

The stability of o-5,5-dimethyl-A’-thiazoline-4-carboxylic acid has been studied under various conditions. In 10 mu cacodylate, pH 6.5, and at 55”C, o-5,5-dimethyld’-thiazoline-4-carboxylic acid (at concentrations lower than 1 mu) is hydrolyzed into N-formyl-n-penicillamine with a half-life of 3 to 4 min. On this basis, it is very unlikely that D-5,5dimethyl-AZ-thiazoline-4-carboxylic acid coul...

This review examines the methods used to study carboxylic acids and the results of such studies on certain acids in freshwater snails. The three areas of carboxylic acid interest considered in this review involve their roles as metabolites, phagostimulants, and biomarkers. The chromatographic and non-chromatographic methods used to study the carboxylic acids in the snails are considered herein....