Plant-based whole foods provide thousands of bioactive metabolites to the human diet that reduce the risk of developing chronic diseases. β-Caryophyllene (CAR) is a common constituent of the essential oil of numerous plants, vegetables, fruits and medicinal herbs, and has been used as a flavouring agent since the 1930 s. Here, we report the antioxidant activity of CAR, its protective effect on ...

The coxsackie and adenovirus receptor (CAR) is a cell adhesion molecule mostly localized to cell-cell contacts in epithelial and endothelial cells. CAR is known to regulate tumor progression, however, its physiological role in keratinocyte migration and proliferation, two essential steps in re-epithelialization during wound healing, has less been investigated. Here we showed that CAR was predom...

Phenobarbital (PB) induces various gene encoding drug/steroid-metabolizing enzymes such as cytochromes P450 (P450s) and transferases. Although the nuclear orphan constitutive active receptor (CAR) has been identified as a key transcription factor that regulates the induction of CYP2B, the full scope of CAR-regulated genes still remains a major question. To this end, reverse transcriptase-polyme...

We present infrared images obtained with the ISOCAM instrument on board the Infrared Space Observatory of two Luminous Blue Variables (AG Car and HR Car). The images were obtained at eight wavelengths between 8.5 and 16 m using the Circular Variable Filters (CVFs), with a pixel size of 6 by 6 arcsec and a total field of view of 192 by 192 arcsec. The nebula around AG Car is clearly resolved. Th...

The rising car usage deriving from growth in jobs and residential population results in air pollution, energy waste and unproductive and unpleasant consumption of people’s time. Public transport cannot be the only answer to this increasing transport demand. Car pooling has emerged to be a viable possibility for reducing private car usage in congested areas. Its actual practice requires a suitab...

Car body deformation modeling plays a very important role in crash accident analyses, as well as in safe car body design. The determination of the energy absorbed by the deformation and the corresponding Energy Equivalent Speed can be of key importance, however their precise determination is a very difficult task. Although, using the results of crash tests, intelligent and soft methods offer an...

A transient heat transfer mathematical model for the prediction of temperature distribution in the car body during primer baking has been developed by considering the thermal radiation and convection in the furnace chamber and transient heat conduction governing equations in the car framework. The car cockpit is considered like a structure with six flat plates, four vertical plates representing...

Although a substantial body of research concurs that most urban areas have a challenge in providing adequate car parking space, there is a scarcity in the literature on how conformity to planning standards that regulates the provision of car parking spaces may be analyzed. This study, therefore, examines the extent to which the planning standards that regulate compliance with the provision of c...

The constitutive androstane receptor (CAR) not only displays a high basal transcriptional activity but also acts as a ligand-dependent transcriptional factor. It is known that CAR exhibits different ligand profiles across species. However, the mechanisms underlying CAR activation by chemicals and the species-specific responses are not fully understood. The objectives of this study are to establ...