The basic aspects of capillary electrophoresis (CE) such as: instrumentation, separation modes and its chief domains of use in forensic analysis are presented. Micellar electrokinetic capillary chromatography (MECC), capillary zone electrophoresis (CZE) and chiral separations – the most often used separation modes in drugs analysis – are described. The main directions of development of CE metho...

The ionization constant (pKa) and limiting ionic mobility of 3-chlorotyrosine (CT) and 3-nitrotyrosine (NT) were determined in capillary zone electrophoresis (CZE) in a wide pH range. Measurements were carried out in a poly(ionic liquid) (PIL) modified capillary at a low pH (1.80-4.00) and a bare fused capillary at an upper pH (3.00-11.00). Electrostatic interaction between analytes and inner w...

Capillary zone electrophoresis proved useful for separating small amounts of both charged and uncharged solutes that are otherwise difficult to analyse. A typical complex mixture that had previously resisted all analytical approaches, including reversed-phase separations, is the products arising from the reaction of free amino acids with aldehydic sugars (Maillard reaction products). By using c...

background: detecting bence-jones protein in urine is essential for determining plasma cell dyscrasia and multiple myeloma. conventionally, acid-heat precipitation assay is used for detecting bence-jones protein in most medical laboratories; however, because of the low accuracy of this test, other more sensitive tests like urine electrophoresis are recommended.  materials and methods: in this s...

Despite the significant advantages of capillary isoelectric focusing over gel isoelectric focusing, widespread acceptance of the technique as a replacement for gel isoelectric focusing has not occurred. Several factors contribute to capillary isoelectric focusing’s slower-than-expected adoption; perhaps the most important are the performance and procedural difficulties introduced when capillary...

Background: Hemoglobin D Iran is frequently misdiagnosed as Hb E or Punjab if only one method of screening used. The objective our study was to highlight the importance using two different techniques in diagnosis a hemoglobin variant, case. Hematological parameters heterozygous and compound β/Hb were also compared. Methods: A descriptive carried out on results 52,379 subjects which part thalass...