نتایج جستجو برای: capillary tissue exchange
تعداد نتایج: 1126028 فیلتر نتایج به سال:
Aquaporins (AQs) increase cell membrane CO(2) diffusivity, and it has been proposed that they may serve as transmembrane channels for CO(2) and other small gas molecules. In addition, it has been hypothesized that voltage-gated H(+) channels located on the apical membrane of the alveolar epithelium contribute to CO(2) elimination by the lung. To test whether these membrane proteins contribute t...
Increasing pulmonary blood flow and the associated rise in capillary perfusion pressure cause capillary recruitment. The resulting increase in capillary volume limits the decrease in capillary transit time. We hypothesize that small species with relatively high resting metabolic rates are more likely to utilize a larger fraction of gas-exchange reserve at rest. Without reserve, we anticipate th...
T HE CAPILLARIES in the lungs, in contrast to capillaries elsewhere in the body, are in effect bathed in air rather than water. There is little histological evidence for a substantial pulmonary interstitial space; instead, the bulk of the lung tissue appears to consist of cells and blood vessels. Perhaps because of these anatomical peculiarities little or no consideration appears to have been g...
The juxtaposition of a dense capillary network to lung epithelial cells is essential for air-blood gas exchange. Defective lung vascular development can result in bronchopulmonary dysplasia and alveolar capillary dysplasia. Although vascular endothelial growth factor A (Vegfa) is required for formation of the lung capillary network, little is known regarding the factors that regulate the densit...
BACKGROUND high-altitude adaptation leads to progressive increase in arterial Pa(O2). In addition to increased ventilation, better arterial oxygenation may reflect improvements in lung gas exchange. Previous investigations reveal alterations at the alveolar-capillary barrier indicative of decreased resistance to gas exchange with prolonged hypoxia adaptation, but how quickly this occurs is unkn...
The fine structure of the lymphatic capillary and the surrounding tissue areas was investigated. Instead of a continuous basal lamina (basement membrane) surrounding the capillary wall, these observations revealed the occurrence of numerous fine filaments that insert on the outer leaflet of the trilaminar unit membrane of the lymphatic endothelium. These filaments appear as individual units, or...
In the field of tissue engineering and regenerative medicine, there is a demand for construction of three-dimensional (3D) organs such as liver, pancreas, and kidney. Although recent advances in tissue engineering allowed us to construct two-dimensional tissues such as skin and cornea, it is still challenging to construct 3D organs. Since these vital organs are complex in structure and contain ...
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