A scanning probe microscope methodology, called resonant difference-frequency atomic force ultrasonic microscopy RDF-AFUM , has been developed. It employs an ultrasonic wave launched from the bottom of a sample while the cantilever of an atomic force microscope, driven at a frequency differing from the ultrasonic frequency by one of the contact resonance frequencies of the cantilever, engages t...

Current progress on the use of dynamic-mode cantilever sensors for biosensing applications is critically reviewed. We summarize their use in biosensing applications to date with focus given to: cantilever size (milli-, micro-, and nano-cantilevers), their geometry, and material used in fabrication. The review also addresses techniques investigated for both exciting and measuring cantilever reso...

Microfabricated cantilever beams have been used in microelectromechanical systems for a variety of sensor and actuator applications. Bimorph cantilevers accurately measure temperature change and heat flux with resolutions several orders of magnitude higher than those of conventional sensors such as thermocouples, semiconductor diodes, as well as resistance and infrared thermometers. The use of ...

Photothermal excitation is a cantilever excitation method that enables stable and accurate operation for dynamic-mode AFM measurements. However, the low excitation efficiency of the method has often limited its application in practical studies. In this study, we propose a method for improving the photothermal excitation efficiency by coating cantilever backside surface near its fixed end with c...

We propose a novel and highly sensitive integrated read-out scheme, capable of detecting sub-nanometre deflections of a cantilever in close proximity to a grated waveguide structure. We discuss modelling results for an SiO2 cantilever to be integrated with an optical cavity defined by a grated Si3N4 waveguide.

The cantilever sensor, which acts as a transducer of reactions between model bacterial cell wall matrix immobilized on its surface and antibiotic drugs in solution, has shown considerable potential in biochemical sensing applications with unprecedented sensitivity and specificity. The drug-target interactions generate surface stress, causing the cantilever to bend, and the signal can be analyze...

cost optimization of the reinforced concrete cantilever soil retaining wall of a given height satisfying some structural and geotechnical design constraints is performed utilizing harmony search and improved harmony search algorithms. the objective function considered is the cost of the structure, and design is based on aci 318-05. this function is minimized subjected to design constraints. a n...

The paper reports on theoretical and experimental results of integrated optical (IO) cavities defined by grated waveguides in Si3N4 and Si, for the accurate detection of cantilever deflection and bulk index changes. Microcantilever-based sensors can be used to detect molecular adsorption, which causes changes in the surface stress [1], leading to deflection of the cantilever. We propose a novel...

For more than two decades, the Atomic Force Microscope (AFM) has provided valuable insights in nanoscale phenomena, and it is now widely employed by scientists from various disciplines. AFMs use a cantilever beam with a sharp tip to scan the surface of a sample both to image it and to perform mechanical testing. Since the AFM measures the de ection of the probe beam, one must rst nd the spring ...

Specific aims of this study are to investigate the mechanism governing surface stress generation associated with chemical or molecular binding on functionalized microcantilevers. Formation of affinity complexes on cantilever surfaces leads to charge redistribution, configurational change and steric hindrance between neighboring molecules resulting in surface stress change and measureable cantil...